Evidence map›Paper›PMID 23697806›Full record

ArticleOpen biology2013

A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Jacqueline Hayles, Valerie Wood, Linda Jeffery, Kwang-Lae Hoe, Dong-Uk Kim, Han-Oh Park, Silvia Salas-Pino, Christian Heichinger, Paul Nurse

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 179 citations in OpenAlex.

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  19. A meiotic driver hijacks an epigenetic reader to disrupt mitosis in noncarrier offspring.Proceedings of the National Academy of Sciences of the United States of America · 2024
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60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 5 countries.

Jacqueline HaylesCell Cycle Laboratory, Cancer Research UK, London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3LY, UK.
Valerie Wood
Linda Jeffery
Kwang-Lae Hoe
Dong-Uk Kim
Han-Oh Park
Silvia Salas-Pino
Christian Heichinger
Paul Nurse
Cancer Research UK · GBChungnam National University · KRKorea Research Institute of Bioscience and Biotechnology · KRRockefeller University · USThe Honourable Society of Lincoln's Inn · GBUniversity of Cambridge · GBUniversity of Zurich · CH

Funding

Cancer Research UK 15699Wellcome Trust 093917
6 · The paper itself

Abstract

To identify near complete sets of genes required for the cell cycle and cell shape, we have visually screened a genome-wide gene deletion library of 4843 fission yeast deletion mutants (95.7% of total protein encoding genes) for their effects on these processes. A total of 513 genes have been identified as being required for cell cycle progression, 276 of which have not been previously described as cell cycle genes. Deletions of a further 333 genes lead to specific alterations in cell shape and another 524 genes result in generally misshapen cells. Here, we provide the first eukaryotic resource of gene deletions, which describes a near genome-wide set of genes required for the cell cycle and cell shape.

Indexed as

Genes, FungalCell CycleComputational BiologyGene DeletionGene Expression Regulation, FungalGenes, cdcGenome, FungalHumansMutagenesisPhenotypeSchizosaccharomycesSchizosaccharomyces pombe ProteinsSchizosaccharomyces pombe Proteinscell cyclecell shapefission yeastgenome-wide gene deletion resource

Identifiers

PMID23697806
PMCPMC3866870
OpenAlexW2153051494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.