ArticleBMC molecular biology2013
Characterization of Stra8 in Southern catfish (Silurus meridionalis): evidence for its role in meiotic initiation.
Article in BMC molecular biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 23 citations in OpenAlex.
- MEIOSIN retains a STRA8-independent activity that contributes to meiotic gene activation across vertebrates.Genes & development · 2026Article
- Dietary xanthophyll improved growth, antioxidant, pigmentation and meat quality in the southern catfish (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- Loss ofFrontiers in cell and developmental biology · 2021Article
- Crosstalk Between Retinoic Acid and Sex-Related Genes Controls Germ Cell Fate and Gametogenesis in Medaka.Frontiers in cell and developmental biology · 2020Article
- Involvement of the retinoic acid signaling pathway in sex differentiation and pubertal development in the European sea bassHeliyon · 2019Article
- Transcriptome Dynamics During Turbot Spermatogenesis Predicting the Potential Key Genes Regulating Male Germ Cell Proliferation and Maturation.Scientific reports · 2018Article
- Transcriptomic analysis of the differentiating ovary of the protogynous ricefield eel Monopterus albus.BMC genomics · 2017Article
- Retinoic acid and meiosis induction in adult versus embryonic gonads of medaka.Scientific reports · 2016Article
- Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.BMC genomics · 2016Article
- Retinoic acid homeostasis through aldh1a2 and cyp26a1 mediates meiotic entry in Nile tilapia (Oreochromis niloticus).Scientific reports · 2015Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRA (retinoic acid) signal pathway has been proved to be required for germ cell meiotic initiation in mammals, aves and amphibians. Stra8 (Stimulated by retinoic acid gene 8) is an important factor in RA signal pathway. However, the role of RA and Stra8 in germ cell meiotic initiation in teleosts is poorly characterized.
resultsIn this study, the full length cDNA of Stra8 was cloned from Southern catfish (Silurus meridionalis), and its spatio-temporal expression profiles were analyzed. The Stra8 cDNA (1606 bp) includes 163 bp 5'-UTR (untranslated region), 456 bp 3'-UTR, and an ORF (open reading frame) of 987 bp, encoding a polypeptide of 328 aa. Phylogenetic analysis revealed its existence in some primitive teleosts, such as Siluriformes and Salmoniformes. Tissue distribution analysis by RT-PCR showed that Stra8 is specifically expressed in gonads. By real-time PCR, in situ hybridization and immunohistochemistry, the highest expression level of Stra8/Stra8 was detected in 50 and 130 dah (day after hatching), the premeiotic stage of germ cells in XX and XY gonads, respectively.
conclusionsOur results suggest that Stra8 might be involved in germ cell meiotic initiation in S. meridionalis as it did in tetrapods.
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