ArticlePloS one2013
Integration of antiretroviral therapy services into antenatal care increases treatment initiation during pregnancy: a cohort study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A Systematic Review of Linkage-to-Care and Antiretroviral Initiation Implementation Strategies in Low- and Middle-Income Countries Across Sub-Saharan Africa.AIDS and behavior · 2022Pooled it
- Approaches to transitioning women into and out of prevention of mother-to-child transmission of HIV services for continued ART: a systematic review.Journal of the International AIDS Society · 2021Pooled it
- Integration of antenatal care services with health programmes in low- and middle-income countries: systematic review.Journal of global health · 2016Pooled it
- A systematic review of interventions to improve prevention of mother-to-child HIV transmission service delivery and promote retention.Journal of the International AIDS Society · 2016Pooled it
- Service guidelines, models, and protocols for integrating rehabilitation services in primary healthcare in Brazil, Russia, India, China, and South Africa: a scoping review.Disability and rehabilitation · 2024Article
- Interventions to enhance healthcare utilisation among pregnant women to reduce maternal mortality in low- and middle-income countries: a review of systematic reviews.BMC public health · 2023Review
- Knowledge and perceptions of primary healthcare providers towards integration of antiretroviral therapy (ART) services at departmental levels at selected health facilities Lira district, Uganda.BMC health services research · 2023Article
- Cultivating a universal understanding of ART adherence: Comments on "A meta-analysis of effectiveness of interventions to improve adherence in pregnant women receiving antiretroviral therapy in sub-Saharan Africa".International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020Article
- Implementation of a PMTCT programme in a high HIV prevalence setting in Johannesburg, South Africa: 2002-2015.Southern African journal of HIV medicine · 2020Article
- Initiation of antiretroviral therapy or antiretroviral prophylaxis in pregnant women living with HIV registered in five townships of Mandalay, Myanmar: A cross sectional study.BMC pregnancy and childbirth · 2019Article
- Uptake of antiretroviral therapy in HIV-positive women ever enrolled into 'prevention of mother to child transmission' programme, Mandalay, Myanmar-a cohort study.BMC pregnancy and childbirth · 2018Article
- Increased prevalence of pregnancy and comparative risk of program attrition among individuals starting HIV treatment in East Africa.PloS one · 2018Article
- Integrated care: learning between high-income, and low- and middle-income country health systems.Health policy and planning · 2017Article
- Overcoming Health System Challenges for Women and Children Living With HIV Through the Global Plan.Journal of acquired immune deficiency syndromes (1999) · 2017Review
- 'First 1000 days' health interventions in low- and middle-income countries: alignment of South African policies with high-quality evidence.Global health action · 2017Article
- Achieving development goals for HIV, tuberculosis and malaria in sub-Saharan Africa through integrated antenatal care: barriers and challenges.BMC medicine · 2016Article
- Barriers and enablers to integrating maternal and child health services to antenatal care in low and middle income countries.BJOG : an international journal of obstetrics and gynaecology · 2016Review
- A New Look at Care in Pregnancy: Simple, Effective Interventions for Neglected Populations.PloS one · 2016Review
- Effectiveness of community-based support for pregnant women living with HIV: a cohort study in South Africa.AIDS care · 2016Article
- Prospects for HIV control in South Africa: a model-based analysis.Global health action · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesInitiation of antiretroviral therapy (ART) during pregnancy is critical to promote maternal health and prevent mother-to-child HIV transmission (PMTCT). The separation of services for antenatal care (ANC) and ART may hinder antenatal ART initiation. We evaluated ART initiation during pregnancy under different service delivery models in Cape Town, South Africa.
methodsA retrospective cohort study was conducted using routinely collected clinic data. Three models for ART initiation in pregnancy were evaluated ART 'integrated' into ANC, ART located 'proximal' to ANC, and ART located some distance away from ANC ('distal'). Kaplan-Meier methods and Poisson regression were used to examine the association between service delivery model and antenatal ART initiation.
resultsAmong 14 617 women seeking antenatal care in the three services, 30% were HIV-infected and 17% were eligible for ART based on CD4 cell count <200 cells/µL. A higher proportion of women started ART antenatally in the integrated model compared to the proximal or distal models (55% vs 38% vs 45%, respectively, global p = 0.003). After adjusting for age and gestation at first ANC visit, women who at the integrated service were significantly more likely to initiate ART antenatally (rate ratio 1.33; 95% confidence interval: 1.09-1.64) compared to women attending the distal model; there was no difference between the proximal and distal models in antenatal ART initiation however (p = 0.704).
conclusionsIntegration of ART initiation into ANC is associated with higher levels of ART initiation in pregnancy. This and other forms of service integration may represent a valuable intervention to enhance PMTCT and maternal health.
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