ArticleThe Journal of biological chemistry2013

An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.

Masaaki Fujita et al.PubMed ↗Full text ↗Publisher ↗

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