ArticleStem cell reviews and reports2013
The impact of commercialisation on public perceptions of stem cell research: exploring differences across the use of induced pluripotent cells, human and animal embryos.
Article in Stem cell reviews and reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- The Ethics of Stem Cell-Based Embryo-Like Structures : A Focus Group Study on the Perspectives of Dutch Professionals and Lay Citizens.Journal of bioethical inquiry · 2024Article
- Give heart cells a beat: An interactive museum exhibit that synchronizes stem cell-derived cardiomyocytes to visitors' heartbeat.Stem cell reports · 2024Article
- Public perceptions and expectations: Disentangling the hope and hype of organoid research.Stem cell reports · 2023Article
- Survey of Japanese researchers and the public regarding the culture of human embryos in vitro beyond 14 days.Stem cell reports · 2023Article
- Benefit sharing in genomic and biobanking research in Uganda: Perceptions of researchers and research ethics committee members.Frontiers in genetics · 2022Article
- Translation and validation of the greek version of a questionnaire measuring patient views on participation in clinical trials.BMC health services research · 2021Article
- Identifying the nature and extent of public and donor concern about the commercialisation of biobanks for genomic research.European journal of human genetics : EJHG · 2021Article
- Stem cell preservation for regenerative therapies: ethical and governance considerations for the health care sector.NPJ Regenerative medicine · 2020Review
- Encouraging Participation And Transparency In Biobank Research.Health affairs (Project Hope) · 2018Article
- Consent for governance in the ethical use of organoids.Nature cell biology · 2018Article
- Factors influencing the willingness to participate in medical research: a nationwide survey in Taiwan.PeerJ · 2018Article
- Predicting Public Attitudes Toward Gene Editing of Germlines: The Impact of Moral and Hereditary Concern in Human and Animal Applications.Frontiers in genetics · 2018Article
- Cell-based therapeutic strategies for replacement and preservation in retinal degenerative diseases.Progress in retinal and eye research · 2017Review
- Citizen expectations of 'academic entrepreneurship' in health research: public science, practical benefit.Health expectations : an international journal of public participation in health care and health policy · 2015Article
- The commercialization of university-based research: Balancing risks and benefits.BMC medical ethics · 2015Review
- Stem cells for spine surgery.World journal of stem cells · 2015Review
- Commercialization and stem cell research: a review of emerging issues.Stem cells and development · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of pluripotent cells that enable stem cell research (SCR) without destroying human embryos is now a leading priority for science. Public and political controversies associated with human embryonic SCR experienced in the recent past should be alleviated if scientists no longer need to harvest cells from human embryos. This research suggests however additional issues needing attention in order to gain the public's trust and support: the use of mouse embryos and the commercialisation of research. Using a representative sample of 2,800 Australians, and an experimental telephone survey design, this research compared levels and predictors of public support for stem cell research across three cell source conditions: human embryo (HE), mouse embryo (ME) and induced pluripotent cells (iPSCs). The results revealed that the public were significantly more likely to support research using iPSCs than HE and ME cells and public compared to private research (regardless of the cell source). There was no significant difference in support for HE compared to ME research, but the former was viewed as more likely to lead to accessible health care benefits and to be associated with more trustworthy scientists. The results of a multimediation structural equation model showed that the primary reason support for SCR significantly dropped in a private compared to public context (i.e., the commercialisation effect) was because public scientists were trusted more than private scientists. This effect was consistent across all three SCR materials, suggesting that the use of mouse embryos or even iPSCs will not reduce the publics' concern with commercialised science. The implications these results have for public acceptance of stem cell and animal research are discussed in relation to possible solutions such as increasing public awareness of the regulation of animal research and benefit sharing.
Indexed as
Identifiers
23695820What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.