ArticleThe Pediatric infectious disease journal2013
Viral etiologies of infant bronchiolitis, croup and upper respiratory illness during 4 consecutive years.
Article in The Pediatric infectious disease journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 4 of them syntheses that pooled it.
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The trial behind it
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Who cites it
92 citing papers in PubMed, 4 syntheses or guidelines pooled it, 211 citations in OpenAlex.
- Diagnostic models predicting paediatric viral acute respiratory infections: a systematic review.BMJ open · 2023Pooled it
- Systematic Literature Review of Respiratory Syncytial Virus Laboratory Testing Practices and Incidence in United States Infants and Children <5 Years of Age.The Journal of infectious diseases · 2022Pooled it
- Hospital utilization rates for influenza and RSV: a novel approach and critical assessment.Population health metrics · 2021Pooled it
- Pooled it
- Comparison of 3 different flow rates of high-flow nasal cannula (1 L/kg/min versus 2 L/kg/min versus 3 L/kg/min) in management of children admitted with bronchiolitis: a randomized controlled trial.European journal of pediatrics · 2025Trial
- Trial
- A multi-center randomized prospective study on the treatment of infant bronchiolitis with interferon α1b nebulization.PloS one · 2020Trial
- Point-of-care lung ultrasound in infants with bronchiolitis in the pediatric emergency department: a prospective study.European journal of pediatrics · 2019Trial
- Trial
- Trial
- Misdiagnosis of bronchiolitis and misuse of antibiotics - experience from the largest paediatric hospital of Bangladesh.Journal of global health · 2026Observational
- A Decade of Croup Management: Guideline Adherence, Practice Variation, and Opportunities for Improvement.Children (Basel, Switzerland) · 2026Article
- Effects of implementing a clinical scoring system on the management of infants with RSV bronchiolitis.Wiener klinische Wochenschrift · 2026Observational
- Article
- The prevalence and role of human respiratory syncytial virus in pediatric respiratory tract infections: a systematic review and meta-analysis of global data.EClinicalMedicine · 2026Article
- The Use of Point-of-Care Tests and Multiplex PCR Tests in the Pediatric Emergency Department Reduces Antibiotic Prescription in Patients with Febrile Acute Respiratory Infections.Pathogens (Basel, Switzerland) · 2025Article
- Seasonal dynamics and genetic diversity of human rhinoviruses in patients with acute respiratory infection in Bangkok in 2024.Archives of virology · 2025Article
- Efficacy and safety of nirsevimab for preventing respiratory syncytial virus infection in infants: an updated systematic review and meta-analysis encompassing 11,001 participants.Proceedings (Baylor University. Medical Center) · 2025Article
- Clinical Impact of Serious Respiratory Disease in Children Under the Age of 2 Years During the 2021-2022 Bronchiolitis Season in England, Scotland, and Ireland.The Journal of infectious diseases · 2024Observational
- Economic Burden of Medically Attended Respiratory Syncytial Virus Infections Among Privately Insured Children Under 5 Years of Age in the USA.Influenza and other respiratory viruses · 2024Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundProspective data on viral etiology and clinical characteristics of bronchiolitis and upper respiratory illness (URI) in infants are limited.
methodsThis prospective cohort enrolled previously healthy term infants during inpatient or outpatient visits for acute URI or bronchiolitis during September to May 2004 to 2008. Illness severity was determined using an ordinal bronchiolitis severity score. Common respiratory viruses were identified by real-time reverse-transcriptase polymerase chain reaction.
resultsOf 648 infants, 67% were enrolled during inpatient visits and 33% during outpatient visits. Seventy percent had bronchiolitis, 3% croup and 27% URI. Among infants with bronchiolitis, 76% had respiratory syncytial virus (RSV), 18% human rhinovirus (HRV), 10% influenza, 2% coronavirus, 3% human metapneumovirus and 1% parainfluenza virus. Among infants with croup, 39% had HRV, 28% parainfluenza virus, 28% RSV, 11% influenza, 6% coronavirus and none human metapneumovirus. Among infants with URI, 46% had HRV, 14% RSV, 12% influenza, 7% coronavirus, 6% parainfluenza virus and 4% human metapneumovirus. Individual viruses exhibited distinct seasonal, demographic and clinical expression.
conclusionsThe most common infections among infants seeking care in unscheduled medical visits for URI or bronchiolitis were RSV and HRV. Demographic differences were observed between patients with different viruses, suggesting that host and viral factors play a role in phenotypic expression of viral illness.
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