ArticleGut pathogens2013
Emerging importance of holobionts in evolution and in probiotics.
Article in Gut pathogens, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Rethinking Conservation in the Anthropocene-The Case of Holobionts.Disease biology, genetics, and socioecology · 2025Article
- Swine Gastrointestinal Microbiota and the Effects of Dietary Amino Acids on Its Composition and Metabolism.International journal of molecular sciences · 2024Review
- GenBank as a source to monitor and analyze Host-Microbiome data.Bioinformatics (Oxford, England) · 2022Article
- Effect of Intervention of Probiotics in Advance on Treg/Th17 in Premature Mice.BioMed research international · 2022Article
- Urbanization Constrains Skin Bacterial Phylogenetic Diversity in Wild Fish Populations and Correlates with the Proliferation of Aeromonads.Microbial ecology · 2021Article
- Plant Holobiont Theory: The Phytomicrobiome Plays a Central Role in Evolution and Success.Microorganisms · 2021Review
- Article
- Interactions within the microbiome alter microbial interactions with host chemical defences and affect disease in a marine holobiont.Scientific reports · 2019Article
- Functional Probiotic Assessment andBioMed research international · 2018Article
- Coastal urbanisation affects microbial communities on a dominant marine holobiont.NPJ biofilms and microbiomes · 2018Article
- Managing the Microbial Community of Marine Fish Larvae: A Holistic Perspective for Larviculture.Frontiers in microbiology · 2018Review
- Beneficial Microorganisms for Corals (BMC): Proposed Mechanisms for Coral Health and Resilience.Frontiers in microbiology · 2017Review
- Detection of Zoonotic Enteropathogens in Children and Domestic Animals in a Semirural Community in Ecuador.Applied and environmental microbiology · 2016Article
- Ancient human microbiomes.Journal of human evolution · 2015Article
- Holobionts: emerging strategy for interventions against infectious diseases, metabolic disorders & cancer.The Indian journal of medical research · 2014Article
- Timely approaches to identify probiotic species of the genus Lactobacillus.Gut pathogens · 2013Article
- Big brains, meat, tuberculosis, and the nicotinamide switches: co-evolutionary relationships with modern repercussions?International journal of tryptophan research : IJTR · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The existence of microbe free animals or plants in nature is virtually impossible as they and plants have a certain degree of symbiotic association with microbes. This symbiotic association leads to the formation of holobiont (host and its symbionts). This mutual coexistence is not merely at the physical or chemical level but also at the genetic level leading to the emergence of the concept of hologenome (gene pool of host and its associated symbionts). The abundance of symbionts with the associated gene diversity contributes to the fitness of the holobiont under varying environmental conditions. The hologenome theory of evolution considers the dynamic holobiont as a single unit for natural selection and provides a more accommodating view of evolution blending Darwinism and Lamarkism. Additionally, holobionts are providing scientific basis to our understanding of the growing importance of probiotics in human health and in disease management.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.