Evidence map›Paper›PMID 23692915›Full record

ArticleInfluenza and other respiratory viruses2013

Outbreak of febrile respiratory illness associated with human adenovirus type 14p1 in Gansu Province, China.

Guohong Huang, Deshan Yu, Zhen Zhu, Hai Zhao, Peng Wang, Gregory C Gray, Lei Meng, Wenbo Xu

Open access · hybridAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
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  12. Molecular and clinical characterization of human adenovirus associated with acute respiratory tract infection in hospitalized children.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020
    Article
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  15. Vaccine development for human mastadenovirus.Journal of thoracic disease · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Guohong HuangChinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Beijing, China; Xinjiang Medical University, Urumqi, China.
Deshan Yu
Zhen Zhu
Hai Zhao
Peng Wang
Gregory C Gray
Lei Meng
Wenbo Xu
Gansu Provincial Center for Disease Control and Prevention · CNNational Institute for Viral Disease Control and Prevention · CNUniversity of Florida Health · USXinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHuman adenovirus (HAdV) type 14 had been infrequently associated with outbreaks of febrile respiratory illness (FRI) until the HAdV-14p1 emerged in 2006 and rapidly spread in the United States. Here, we report an outbreak of FRI caused by HadV-14p1 that occurred in 2011 at a primary and middle school in China.

designThe basic information of the outbreak was recored; throat swabs were collected from 17 patients, polymerase chain reaction, A549 cell culture, and sequencing were used to identify the pathogen of the outbreak..

resultsTotal of 43 students were infected in this outbreak. Boys were more than girls. We identified 11 HAdV-positive specimens and 6 HAdV isolates. Genetic analysis showed that the complete hexon, fiber, and E1A sequences of isolates were nearly 100% identical with other HAdV-14p1 sequences deposited in GenBank.

conclusionsHadV-14p1 has caused outbreaks of pneumonia and mortality among adults in the United States and Europe. It may cause similar conditions among Chinese adults due to poor hygiene and sanitation. It seems prudent for China to develop a national surveillance system to determine the etiology of severe respiratory diseases and deaths among adults and school-aged children.

Indexed as

Disease OutbreaksAdenoviridae InfectionsAdenoviruses, HumanAdolescentAdultChildChinaDNA, ViralFemaleFeverHumansMaleMolecular Sequence DataPharynxPolymerase Chain ReactionRespiratory Tract InfectionsDNA, Viraladenovirusepidemiologyrespiratory tract infections

Identifiers

PMID23692915
PMCPMC3933759
OpenAlexW2003135888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.