Evidence map›Paper›PMID 23692141›Full record

ArticleThe Journal of organic chemistry2013

Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.

Baudouin Gerard, Maurice D Lee, Sivaraman Dandapani, Jeremy R Duvall, Mark E Fitzgerald, Sarathy Kesavan, Jason T Lowe, Jean-Charles Marié, Bhaumik A Pandya, Byung-Chul Suh and 8 more

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Fused-Linked and Spiro-Linked N-Containing Heterocycles.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Diversity-oriented synthesis of glycomimetics.Communications chemistry · 2021
    Article
  6. Novel tricyclic glycal-basedMedChemComm · 2018
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Baudouin GerardChemical Biology Platform, The Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
Maurice D Lee
Sivaraman Dandapani
Jeremy R Duvall
Mark E Fitzgerald
Sarathy Kesavan
Jason T Lowe
Jean-Charles Marié
Bhaumik A Pandya
Byung-Chul Suh
Morgan Welzel O'Shea
Michael Dombrowski
Diane Hamann
Berenice Lemercier
Tiffanie Murillo
Lakshmi B Akella
Michael A Foley
Lisa A Marcaurelle

Funding

The Incubator ProjectP50GM069721 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SCHREIBER, STUART L · 2003 to 2012
$21.3M
Discovery Pipeline (2 of 4)RL1CA133834 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GOLUB, TODD R. · 2007 to 2011
$9.9M
Driving Medical Projects (4 of 4)RL1GM084437 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SCOLNICK, EDWARD MARK · 2007 to 2011
$5.9M
Target ID (3 of 4)RL1HG004671 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SCHREIBER, STUART L · 2007 to 2011
$5.8M
Genomics Based Drug Discovery (1 of 4)UL1DE019585 · NIDCR · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SCHERER, CHRISTINA ANN · 2008 to 2011
$1.5M
NCI NIH HHS RL1 CA133834NCI NIH HHS U54 RL1CA133834NHGRI NIH HHS RL1 HG004671NHGRI NIH HHS RL1HG004671NIDCR NIH HHS UL1 DE019585NIDCR NIH HHS UL1DE019585NIGMS NIH HHS P50 GM069721NIGMS NIH HHS RL1 GM084437NIGMS NIH HHS RL1GM084437
6 · The paper itself

Abstract

A diversity-oriented synthesis (DOS) strategy was developed for the synthesis of stereochemically diverse fused-ring systems containing a pyran moiety. Each scaffold contains an amine and methyl ester for further diversification via amine capping and amide coupling. Scaffold diversity was evaluated in comparison to previously prepared scaffolds by a shape-based principal moments of inertia (PMI) analysis.

Indexed as

GlycosidesMolecular ConformationPyransStereoisomerismGlycosidesPyrans

Identifiers

PMID23692141
PMCPMC3752688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.