Evidence map›Paper›PMID 23691503›Full record

ArticleBioMed research international2013

Effect of tea (Camellia sinensis) and olive (Olea europaea L.) leaves extracts on male mice exposed to diazinon.

Atef M Al-Attar, Isam M Abu Zeid

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. The effect of diazinon on blood glucose homeostasis: a systematic and meta-analysis study.Environmental science and pollution research international · 2021
    Pooled it
  3. Impact ofSaudi journal of biological sciences · 2023
    Article
  4. Article
  5. Protective effects of olive leaf extract against reproductive toxicity of the lead acetate in rats.Environmental science and pollution research international · 2021
    Article
  6. Alleviation of Malathion Toxicity Effect byPlants (Basel, Switzerland) · 2021
    Article
  7. Olive leaf extract modulates glycerol-induced kidney and liver damage in rats.Environmental science and pollution research international · 2020
    Article
  8. Article
  9. The aqueous extract ofRSC advances · 2019
    Article
  10. Article
  11. Effect ofSaudi journal of biological sciences · 2019
    Article
  12. Article
  13. Article
  14. Effects ofDiabetes, metabolic syndrome and obesity : targets and therapy · 2018
    Article
  15. Article
  16. Potential contribution of insecticide exposure and development of obesity and type 2 diabetes.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2017
    Review
  17. Article
  18. Phytochemistry and Pharmacological Studies ofEvidence-based complementary and alternative medicine : eCAM · 2017
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Atef M Al-AttarDepartment of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah 21323, Saudi Arabia. atef_a_2000@yahoo.com
Isam M Abu Zeid
King Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was aimed to evaluate the effects of tea and olive leaves extracts and their combination in male mice intoxicated with a sublethal concentration of diazinon. Exposure of mice to 6.5 mg/kg body weight of diazinon for seven weeks resulted in statistical increases of serum alanine aminotransferase, aspartate aminotransferase, gamma glutamyl transferase, alkaline phosphatase, creatine kinase, creatinine, glucose, triglycerides, and cholesterol, while the value of serum total protein was declined. Treating diazinon-intoxicated mice with tea and olive leaves extracts or their combination significantly attenuated the severe alterations in these hematobiochemical parameters. Moreover, the results indicated that the supplementation with combination of tea and olive leaves extracts led to more attenuation effect against diazinon toxicity. Additionally, these new findings suggest that the effect of tea and olive leaves extracts and their combination against toxicity of diazinon may be due to antioxidant properties of their chemical constituents. Finally, the present study indicated that the extracts of tea and olive leaves and their combination can be considered as promising therapeutic agents against hepatotoxicity, cardiotoxicity, nephrotoxicity, and metabolic disorders induced by diazinon and maybe by other toxicants and pathogenic factors.

Indexed as

Environmental ExposureAlanine TransaminaseAlkaline PhosphataseAnimalsAspartate AminotransferasesBlood GlucoseCamellia sinensisCholesterolCreatine KinaseCreatinineDiazinongamma-GlutamyltransferaseMaleMiceOleaPlant ExtractsAlanine TransaminaseAlkaline PhosphataseAspartate AminotransferasesBlood GlucoseCholesterolCreatine KinaseCreatinineDiazinongamma-GlutamyltransferasePlant ExtractsTriglycerides

Identifiers

PMID23691503
PMCPMC3652132
OpenAlexW1996055719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.