ArticleInternational journal of hepatology2013
Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context.
Article in International journal of hepatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- The enigma of glutamine synthetase and b-catenin expression in hepatocellular adenoma in familial adenomatous polyposis coli.Virchows Archiv : an international journal of pathology · 2024Article
- Integrated genotype-phenotype analysis of familial adenomatous polyposis-associated hepatocellular adenomas.Virchows Archiv : an international journal of pathology · 2024Article
- Phenotype or Genotype: Decision-Making Dilemmas in Hepatocellular Adenoma.Hepatology (Baltimore, Md.) · 2019Article
- New MRI features improve subtype classification of hepatocellular adenoma.European radiology · 2019Article
- Sexual dimorphism in hepatitis B and C and hepatocellular carcinoma.Seminars in immunopathology · 2019Review
- Hepatocellular adenoma: when and how to treat? Update of current evidence.Therapeutic advances in gastroenterology · 2016Review
- Gd-EOB-DTPA-Enhanced Magnetic Resonance Findings of a Giant Inflammatory Hepatocellular Adenoma: a Case Report and Review of the Literature.Journal of gastrointestinal cancer · 2015Review
- [Hepatocellular tumours in noncirrhotic liver tissue].Der Pathologe · 2015Review
- Current Proceedings in the Molecular Dissection of Hepatocellular Adenomas: Review and Hands-on Guide for Diagnosis.International journal of molecular sciences · 2015Review
- Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice.Journal of translational medicine · 2015Article
- Hepatocellular adenoma with malignant transformation in male patients with non-cirrhotic livers.Chinese journal of cancer · 2015Article
- Hepatocellular adenoma management: advances but still a long way to go.Hepatic oncology · 2015Review
- Is This Patient's Liver Mass Cancer?Journal of the advanced practitioner in oncologyArticle
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Europe and North America, hepatocellular adenomas (HCA) occur, classically, in middle-aged woman taking oral contraceptives. Twenty percent of women, however, are not exposed to oral contraceptives; HCA can more rarely occur in men, children, and women over 65 years. HCA have been observed in many pathological conditions such as glycogenosis, familial adenomatous polyposis, MODY3, after male hormone administration, and in vascular diseases. Obesity is frequent particularly in inflammatory HCA. The background liver is often normal, but steatosis is a frequent finding particularly in inflammatory HCA. The diagnosis of HCA is more difficult when the background liver is fibrotic, notably in vascular diseases. HCA can be solitary, or multiple or in great number (adenomatosis). When nodules are multiple, they are usually of the same subtype. HNF1 α -inactivated HCA occur almost exclusively in woman. The most important point of the classification is the identification of β -catenin mutated HCA, a strong argument to identify patients at risk of malignant transformation. Some HCA already present criteria indicating malignant transformation. When the whole nodule is a hepatocellular carcinoma, it is extremely difficult to prove that it is the consequence of a former HCA. It is occasionally difficult to identify HCA remodeled by necrosis or hemorrhage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.