ArticleTuberculosis research and treatment2013
Psychiatric morbidity and other factors affecting treatment adherence in pulmonary tuberculosis patients.
Article in Tuberculosis research and treatment, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
101 citing papers in PubMed, 8 syntheses or guidelines pooled it, 193 citations in OpenAlex.
- Prevalence and Predictors of Anxiety among Tuberculosis Patients in India: A Systematic Review and Meta-Analysis.Journal of epidemiology and global health · 2026Pooled it
- Pooled it
- Characteristics of isoniazid-induced psychosis: a systematic review of case reports and case series.European journal of clinical pharmacology · 2024Pooled it
- Prevalence of Tuberculosis and Mental Disorders Comorbidity: A Systematic Review and Meta-analysis.Journal of immigrant and minority health · 2022Pooled it
- The relationship between mental health and risk of active tuberculosis: a systematic review.BMJ open · 2022Pooled it
- Tuberculosis related disability: a systematic review and meta-analysis.BMC medicine · 2021Pooled it
- Association between tuberculosis and depression on negative outcomes of tuberculosis treatment: A systematic review and meta-analysis.PloS one · 2020Pooled it
- Pharmacological or non-pharmacological interventions for treatment of common mental disorders associated with Tuberculosis: A systematic review.Chronic respiratory diseasePooled it
- Factors Associated With Discontinuation of Tuberculosis Preventive Treatment: Post Hoc Analysis of 2 Randomized, Controlled Trials.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Trial
- Qualitative study of patient experiences of mental distress during TB investigation and treatment in Zambia.BMC psychology · 2022Trial
- Depressive symptoms and HIV risk behaviours among adolescents enrolled in the HPTN071 (PopART) trial in Zambia and South Africa.PloS one · 2022Trial
- Trial
- Psychosocial Interventions for Improving Treatment Adherence in Tuberculosis Patients: A Scoping Review of Evidence-Based Approaches.Advances in respiratory medicine · 2026Article
- Mental health management in the context of TB care in the WHO European Region: a consensus statement.IJTLD open · 2026Review
- Article
- Depression and social support as mediators between coping strategies and quality of life in pulmonary tuberculosis patients.BMC psychology · 2026Article
- Reframing TB Care: A Perspective on Multimorbidity-Centered Care for People with TB.Tropical medicine and infectious disease · 2026Article
- Designing integrated care models for mental health and tuberculosis in Pune, India: A formative qualitative study of patient, caregiver and provider perspectives.Global mental health (Cambridge, England) · 2026Article
- Pulmonary tuberculosis in diabetes: Exploring the intersection and impact on mental health.World journal of clinical cases · 2025Review
- Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the overall prevalence of TB remains high among certain population groups, there is growing awareness of psychiatric comorbidity, especially depression and its role in the outcome of the disease. The paper attempts a holistic approach to the effects of psychiatric comorbidity to the natural history of tuberculosis. In order to investigate factors associated with medication nonadherence among patients suffering from tuberculosis, with emphasis on psychopathology as a major barrier to treatment adherence, we performed a systematic review of the literature on epidemiological data and past medical reviews from an historical perspective, followed by theoretical considerations upon the relationship between psychiatric disorders and tuberculosis. Studies reporting high prevalence rates of psychiatric comorbidity, especially depression, as well as specific psychological reactions and disease perceptions and reviews indicating psychiatric complications as adverse effects of anti-TB medication were included. In sum, data concerning factors affecting medication nonadherence among TB patients suggested that better management of comorbid conditions, especially depression, could improve the adherence rates, serving as a framework for the effective control of tuberculosis, but further studies are necessary to identify the optimal way to address such issues among these patients.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.