ArticleInternational journal of hypertension2013
Endothelial activation microparticles and inflammation status improve with exercise training in african americans.
Article in International journal of hypertension, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 47 citations in OpenAlex.
- Intradialytic cycling does not exacerbate microparticles or circulating markers of systemic inflammation in haemodialysis patients.European journal of applied physiology · 2022Trial
- Effects of 8-Week Hatha Yoga Training on Metabolic and Inflammatory Markers in Healthy, Female Chinese Subjects: A Randomized Clinical Trial.BioMed research international · 2016Trial
- A standardized exercise intervention differentially affects premenopausal and postmenopausal African-American women.Menopause (New York, N.Y.) · 2014Trial
- Socioeconomic status as a potential mediator of arterial aging in marginalized ethnic and racial groups: current understandings and future directions.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Review
- Role of circulating microparticles and cytokines in periodontitis associated with diabetes.Frontiers in medicine · 2024Article
- Extracellular Vesicles in Metabolic and Vascular Insulin Resistance.Journal of vascular research · 2024Review
- Effects of Exercise on Circulating Extracellular Vesicles in Cardiovascular Disease.Advances in experimental medicine and biology · 2023Article
- The Potential Prognostic, Diagnostic and Therapeutic Targets for Recurrent Arrhythmias in Patients with Coronary Restenosis and Reocclusions After Coronary Stenting.Current pharmaceutical design · 2022Article
- Article
- Circulating microparticle concentrations across acute and chronic cardiovascular disease conditions.Physiological reports · 2020Article
- Interval Exercise Lowers Circulating CD105 Extracellular Vesicles in Prediabetes.Medicine and science in sports and exercise · 2020Article
- Type 2 diabetes and older age contribute to elevated plasma microparticle concentrations independent of chronic stroke.Experimental physiology · 2018Article
- Exercise-Derived Microvesicles: A Review of the Literature.Sports medicine (Auckland, N.Z.) · 2018Review
- Effects of circuit exercise training on vascular health and blood pressure.Preventive medicine reports · 2018Article
- Extracellular Vesicles: A Novel Target for Exercise-Mediated Reductions in Type 2 Diabetes and Cardiovascular Disease Risk.Journal of diabetes research · 2018Review
- Immune-regulating effects of exercise on cigarette smoke-induced inflammation.Journal of inflammation research · 2018Review
- Physical activity, immune function and inflammation in kidney patients (the PINK study): a feasibility trial protocol.BMJ open · 2017Article
- Differential Response to Exercise in African Americans with High Levels of Inflammation.Ethnicity & disease · 2017Article
- Systemic FDiversity and equality in health and care · 2017Article
- Circulating Endothelial Microparticles: A Key Hallmark of Atherosclerosis Progression.Scientifica · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 1 country.
Funding
Abstract
African Americans have the highest prevalence of hypertension in the world which may emanate from their predisposition to heightened endothelial inflammation. The purpose of this study was to determine the effects of a 6-month aerobic exercise training (AEXT) intervention on the inflammatory biomarkers interleukin-10 (IL-10), interleukin-6 (IL-6), and endothelial microparticle (EMP) CD62E+ and endothelial function assessed by flow-mediated dilation (FMD) in African Americans. A secondary purpose was to evaluate whether changes in IL-10, IL-6, or CD62E+ EMPs predicted the change in FMD following the 6-month AEXT intervention. A pre-post design was employed with baseline evaluation including office blood pressure, FMD, fasting blood sampling, and graded exercise testing. Participants engaged in 6 months of AEXT. Following the AEXT intervention, all baseline tests were repeated. FMD significantly increased, CD62E+ EMPs and IL-6 significantly decreased, and IL-10 increased but not significantly following AEXT. Changes in inflammatory biomarkers did not significantly predict the change in FMD. The change in VO2 max significantly predicted the change in IL-10. Based on these results, AEXT may be a viable, nonpharmacological method to improve inflammation status and endothelial function and thereby contribute to risk reduction for cardiovascular disease in African Americans.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.