ArticlePloS one2013
Quantitative proteomic analysis of cell cycle of the dinoflagellate Prorocentrum donghaiense (Dinophyceae).
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 50 citations in OpenAlex.
- RNA-Binding Proteins in Dinoflagellates.International journal of molecular sciences · 2026Review
- Multi-Omics Profiling Reveals Resource Allocation and Acclimation Strategies to Temperature Changes in a Marine Dinoflagellate.Applied and environmental microbiology · 2022Article
- Expression Patterns of the Heat Shock Protein 90 (Hsp90) Gene Suggest Its Possible Involvement in Maintaining the Dormancy of Dinoflagellate Resting Cysts.International journal of molecular sciences · 2021Article
- Transcriptome and metabolome analyses of cold and darkness-induced pellicle cysts of Scrippsiella trochoidea.BMC genomics · 2021Article
- Differentiating Two Closely RelatedToxins · 2020Article
- Production of high-quality two-dimensional gel electrophoresis profile for marine medaka samples by using Trizol-based protein extraction approaches.Proteome science · 2020Article
- Cell cycle regulation of the mixotrophic dinoflagellate Dinophysis acuminata: Growth, photosynthetic efficiency and toxin production.Harmful algae · 2019Article
- Transcriptomic Responses to Thermal Stress and Varied Phosphorus Conditions inMicroorganisms · 2019Article
- Dinoflagellate nucleus contains an extensive endomembrane network, the nuclear net.Scientific reports · 2019Article
- Evaluation of the Use of TRIzol-Based Protein Extraction Approach for Gel-Based Proteomic Analysis of Dried Seafood Products and Chinese Tonic Foods.International journal of molecular sciences · 2018Article
- iTRAQ-Based Quantitative Proteomic Analysis of a Toxigenic DinoflagellateFrontiers in microbiology · 2018Article
- Enhancement of Non-photochemical Quenching as an Adaptive Strategy under Phosphorus Deprivation in the DinoflagellateFrontiers in microbiology · 2017Article
- Transcriptomic Analyses ofFrontiers in microbiology · 2017Article
- Isolation, phenotypic characterization and genome wide analysis of aBiotechnology for biofuels · 2017Article
- Review
- Comparative Transcriptomic Analysis Reveals Novel Insights into the Adaptive Response ofFrontiers in microbiology · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dinoflagellates are the major causative agents of harmful algal blooms in the coastal zone, which has resulted in adverse effects on the marine ecosystem and public health, and has become a global concern. Knowledge of cell cycle regulation in proliferating cells is essential for understanding bloom dynamics, and so this study compared the protein profiles of Prorocentrum donghaiense at different cell cycle phases and identified differentially expressed proteins using 2-D fluorescence difference gel electrophoresis combined with MALDI-TOF-TOF mass spectrometry. The results showed that the synchronized cells of P. donghaiense completed a cell cycle within 24 hours and cell division was phased with the diurnal cycle. Comparison of the protein profiles at four cell cycle phases (G1, S, early and late G2/M) showed that 53 protein spots altered significantly in abundance. Among them, 41 were identified to be involved in a variety of biological processes, e.g. cell cycle and division, RNA metabolism, protein and amino acid metabolism, energy and carbon metabolism, oxidation-reduction processes, and ABC transport. The periodic expression of these proteins was critical to maintain the proper order and function of the cell cycle. This study, to our knowledge, for the first time revealed the major biological processes occurring at different cell cycle phases which provided new insights into the mechanisms regulating the cell cycle and growth of dinoflagellates.
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