Evidence map›Paper›PMID 23691005›Full record

ArticlePloS one2013

Neighborhood disadvantage, neighborhood safety and cardiometabolic risk factors in African Americans: biosocial associations in the Jackson Heart study.

Cheryl R Clark, Mark J Ommerborn, DeMarc A Hickson, Kya N Grooms, Mario Sims, Herman A Taylor, Michelle A Albert

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 2 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Multilevel resilience resources and cardiovascular disease in the United States: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022
    Pooled it
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  6. Racial/ethnic discrimination and racial trauma: Concurrent evaluation among Black adults who smoke in the United States.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
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  8. A Neighborhood-Level Hispanic Paradox: The Interaction among Hispanic Density, Neighborhood Disadvantage, and Survival in Patients with Breast Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
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  9. Social Inequities in Cardiovascular Disease Risk Factors at Multiple Levels Persist Among Mothers in Texas.International journal of environmental research and public health · 2025
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  13. Population-Level Gaps in Coronary Artery Disease Care: A Focused Review.Methodist DeBakey cardiovascular journal · 2025
    Review
  14. Social Genomic Determinants of Health: Understanding the Molecular Pathways by Which Neighborhood Disadvantage Affects Cancer Outcomes.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Review
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Cheryl R ClarkDivision of General Medicine and Primary Care, Brigham and Women's-Faulkner Hospitalist Program, Boston, Massachusetts, USA. crclark@partners.org
Mark J Ommerborn
DeMarc A Hickson
Kya N Grooms
Mario Sims
Herman A Taylor
Michelle A Albert
Brigham and Women's Hospital · USUniversity of Mississippi Medical Center · USHoward University · USJackson State University · US

Funding

JACKSON HEART STUDY--EXAM CENTERN01HC095171 · HC · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI JONES, DANIEL W · 1999 to 2001
$4.6M
Geographic Variation in Cardiovascular Inflammation in Middle-aged & Elderly PopuK08AG032357 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI CLARK, CHERYL RENEE · 2009 to 2013
$634k
JACKSON HEART STUDY--TRAINING CENTERN01HC095172 · HC · TOUGALOO COLLEGE · PI SRINIVASAN, ASOKA · 1999 to 2001
$516k
JACKSON HEART STUDY-N01HC95170N01HC095170 · HC · JACKSON STATE UNIVERSITY · PI TAYLOR, HERMAN ALFRED · 1999 to 2006
$20k
NHLBI NIH HHS K01HL08468-05NHLBI NIH HHS N01 HC095170NHLBI NIH HHS N01 HC095171NHLBI NIH HHS N01 HC095172NHLBI NIH HHS N01-HC-95170NHLBI NIH HHS N01-HC-95171NHLBI NIH HHS N01-HC-95172NIA NIH HHS K08 AG032357NIA NIH HHS K08AG032357
6 · The paper itself

Abstract

objectiveWe examined associations between neighborhood socioeconomic disadvantage, perceived neighborhood safety and cardiometabolic risk factors, adjusting for health behaviors and socioeconomic status (SES) among African Americans.

methodsStudy participants were non-diabetic African Americans (n = 3,909) in the baseline examination (2000-2004) of the Jackson Heart Study. We measured eight risk factors: the metabolic syndrome, its five components, insulin resistance and cardiovascular inflammation. We assessed neighborhood socioeconomic disadvantage with US Census 2000 data. We assessed perceived neighborhood safety, health behaviors and SES via survey. We used generalized estimating equations to estimate associations with a random intercept model for neighborhood effects.

resultsAfter adjustment for health behaviors and SES, neighborhood socioeconomic disadvantage was associated with the metabolic syndrome in women (PR 1.13, 95% CI 1.01, 1.27). Lack of perceived safety was associated with elevated glucose (OR 1.36, 95% CI 1.03, 1.80) and waist circumference (PR 1.06, 95% CI 1.02, 1.11) among women, and with elevated glucose (PR 1.30, 95% CI 1.02, 1.66) and insulin resistance (PR 1.25, 95% CI 1.08, 1.46) among men.

conclusionsNeighborhood socioeconomic disadvantage and perceived safety should be considered as targets for intervention to reduce cardiometabolic risks among African Americans.

Indexed as

SafetySocioeconomic FactorsAdultAgedAged, 80 and overBlack or African AmericanCross-Sectional StudiesFemaleHealth BehaviorHumansMaleMetabolic SyndromeMiddle AgedMultivariate AnalysisResidence CharacteristicsRisk Factors

Identifiers

PMID23691005
PMCPMC3653956
OpenAlexW2026008967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.