ArticleJournal of allergy2013
Use of animal models to investigate major allergens associated with food allergy.
Article in Journal of allergy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 53 citations in OpenAlex.
- Histamine-releasing factor enhances food allergy.The Journal of clinical investigation · 2017Trial
- Mouse Models of Food Allergies: Where Do They Take Us?Clinical reviews in allergy & immunology · 2026Review
- Development of an intestinal allergy model to evaluate the initial introduction of infant rice cereal.NPJ science of food · 2025Article
- Oral and Skin Sensitisation to Peanut Show Different Immunological Features in Brown Norway Rats.Scandinavian journal of immunology · 2025Article
- Transglutaminase-Cross-Linked Tofu Suppressed Soybean-Induced Allergic Reactions by Enhancing Intestinal Mucosa Immune Tolerance.Foods (Basel, Switzerland) · 2024Article
- New Insights into the Role of PD-1 and Its Ligands in Allergic Disease.International journal of molecular sciences · 2021Review
- Alteration of Intestinal Microbiota Composition in Oral Sensitized C3H/HeJ Mice Is Associated With Changes in Dendritic Cells and T Cells in Mesenteric Lymph Nodes.Frontiers in immunology · 2021Article
- Food allergy promotes a Th2/Th17 response that drives house dust mite-induced allergic airway inflammation in humanized mice.Clinical and experimental immunology · 2020Article
- Article
- IgE reactivity to fish allergens from Pacific cod (Gadus macrocephalus) in atopic dogs.BMC veterinary research · 2020Article
- Oral Immunotherapy Using Probiotic Ice Cream Containing Recombinant Food-GradeJournal of immunology research · 2020Article
- Specific Polyunsaturated Fatty Acids Can ModulateFrontiers in immunology · 2020Article
- A swine model of soy protein-induced food allergenicity: implications in human and swine nutrition.Animal frontiers : the review magazine of animal agriculture · 2019Article
- Aeroallergens ExacerbateJournal of immunology (Baltimore, Md. : 1950) · 2018Article
- Enhancing the Safety and Efficacy of Food Allergy Immunotherapy: a Review of Adjunctive Therapies.Clinical reviews in allergy & immunology · 2018Review
- Expression of Colocasia esculenta tuber agglutinin in Indian mustard provides resistance against Lipaphis erysimi and the expressed protein is non-allergenic.Plant cell reports · 2018Article
- Mechanism for initiation of food allergy: Dependence on skin barrier mutations and environmental allergen costimulation.The Journal of allergy and clinical immunology · 2018Article
- Gut Mucosal Antibody Responses and Implications for Food Allergy.Frontiers in immunology · 2018Review
- Hypoallergenic Variant of the Major Egg White Allergen Gal d 1 Produced by Disruption of Cysteine Bridges.Nutrients · 2017Article
- Toll-like receptor 2 activators modulate oral tolerance in mice.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Food allergy is an emerging epidemic that affects all age groups, with the highest prevalence rates being reported amongst Western countries such as the United States (US), United Kingdom (UK), and Australia. The development of animal models to test various food allergies has been beneficial in allowing more rapid and extensive investigations into the mechanisms involved in the allergic pathway, such as predicting possible triggers as well as the testing of novel treatments for food allergy. Traditionally, small animal models have been used to characterise immunological pathways, providing the foundation for the development of numerous allergy models. Larger animals also merit consideration as models for food allergy as they are thought to more closely reflect the human allergic state due to their physiology and outbred nature. This paper will discuss the use of animal models for the investigation of the major food allergens; cow's milk, hen's egg, and peanut/other tree nuts, highlight the distinguishing features of each of these models, and provide an overview of how the results from these trials have improved our understanding of these specific allergens and food allergy in general.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.