ArticleJournal of dental research2013
Sleep apnea symptoms and risk of temporomandibular disorder: OPPERA cohort.
Article in Journal of dental research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed, 3 syntheses or guidelines pooled it, 163 citations in OpenAlex.
- Obesity and temporomandibular joint disorders: a systematic review and meta-analysis.BMC oral health · 2023Pooled it
- Obesity and pain: a systematic review.International journal of obesity (2005) · 2020Pooled it
- Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males.Pain · 2019Pooled it
- Effects of different treatments for obstructive sleep apnea on temporomandibular joint: a randomized clinical trial.BMC oral health · 2024Trial
- Oral appliance therapy versus nasal continuous positive airway pressure in obstructive sleep apnea: A randomized, placebo-controlled trial on temporomandibular side-effects.Clinical and experimental dental research · 2020Trial
- Recognition of Obstructive Sleep Apnea: An Exploratory Bayesian Modeling Analysis.Journal of personalized medicine · 2026Article
- Involvement of peripheral and central sensitization in prolonged mechanical allodynia of the tongue in a rat.Odontology · 2026Article
- Article
- Association of Sleep Disorders with Temporomandibular Joint Pain Dysfunction Syndrome.Journal of pharmacy & bioallied sciences · 2026Article
- Prevalence of Temporomandibular Disorders in Obstructive Sleep Apnea Patients and Relationship Between Temporomandibular Disorder Phenotypes and Severity of Sleep Apnea: An Observational Study.Journal of pharmacy & bioallied sciences · 2025Article
- Associations between temporomandibular disorders/bruxism and head and neck pains: a bidirectional Mendelian randomization study.Journal of oral & facial pain and headache · 2025Article
- Causal effects of sleep behaviors on temporomandibular disorders and pain: a bidirectional mendelian randomization study.Journal of oral & facial pain and headache · 2025Article
- Orofacial pain/headache interlaced to insomnia, sleep apnea and periodic limb movement during sleep/restless leg syndrome: a critical and comprehensive review with insights into social determinants.Journal of oral & facial pain and headache · 2025Review
- Oral Health-related Quality of Life and Daytime Sleepiness in Students.Oral health & preventive dentistry · 2025Article
- The Therapeutic Potential of Cannabidiol in the Management of Temporomandibular Disorders and Orofacial Pain.Pharmaceutics · 2025Review
- Unmasking the hidden risks: clinical implications of 4 premolar extraction orthodontics on health and upper airway dynamics.Evidence-based dentistry · 2025Article
- Morphological changes in temporomandibular joint architecture in patients with temporomandibular disorders: systematic review protocol.BMJ open · 2024Article
- Exploring the causal effects of sleep characteristics on TMD-related pain: a two-sample Mendelian randomization study.Clinical oral investigations · 2024Article
- Disclosure orthodontic and TMD - new study.Evidence-based dentistry · 2024Article
- Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 1 country.
Funding
Abstract
The authors tested the hypothesis that obstructive sleep apnea (OSA) signs/symptoms are associated with the occurrence of temporomandibular disorder (TMD), using the OPPERA prospective cohort study of adults aged 18 to 44 years at enrollment (n = 2,604) and the OPPERA case-control study of chronic TMD (n = 1,716). In both the OPPERA cohort and case-control studies, TMD was examiner determined according to established research diagnostic criteria. People were considered to have high likelihood of OSA if they reported a history of sleep apnea or ≥ 2 hallmarks of OSA: loud snoring, daytime sleepiness, witnessed apnea, and hypertension. Cox proportional hazards regression estimated hazard ratios (HRs) and 95% confidence limits (CL) for first-onset TMD. Logistic regression estimated odds ratios (OR) and 95% CL for chronic TMD. In the cohort, 248 individuals developed first-onset TMD during the median 2.8-year follow-up. High likelihood of OSA was associated with greater incidence of first-onset TMD (adjusted HR = 1.73; 95% CL, 1.14, 2.62). In the case-control study, high likelihood of OSA was associated with higher odds of chronic TMD (adjusted OR = 3.63; 95% CL, 2.03, 6.52). Both studies supported a significant association of OSA symptoms and TMD, with prospective cohort evidence finding that OSA symptoms preceded first-onset TMD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.