Evidence map›Paper›PMID 23690272›Full record

ArticleObesity surgery2013

Sleep-disordered breathing and postoperative outcomes after bariatric surgery: analysis of the nationwide inpatient sample.

Babak Mokhlesi, Margaret D Hovda, Benjamin Vekhter, Vineet M Arora, Frances Chung, David O Meltzer

Open access · greenAbstract read
In one paragraph

Article in Obesity surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 5 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 5 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Pooled it
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  15. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Babak MokhlesiSleep Disorders Center and the Section of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, 5841 S. Maryland Ave MC6076, Chicago, IL, 60637, USA, bmokhles@medicine.bsd.uchicago.edu.
Margaret D Hovda
Benjamin Vekhter
Vineet M Arora
Frances Chung
David O Meltzer
University of Chicago · USUniversity Health Network · CA

Funding

TRANSLATIONAL RESEARCH UNIVERSITY OF CHICAGO: CLINICAL TRIALSUL1RR024999 · NCRR · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2007 to 2011
$25.3M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI Ronald T. Ackermann, MARSHALL H CHIN · 2011 to 2026
$10.0M
Research and Mentoring in Cost-effectiveness and Hospital-based Elder CareK24AG031326 · NIA · UNIVERSITY OF CHICAGO · PI MELTZER, DAVID O · 2008 to 2012
$906k
Environment and Perceived Control: Improving Sleep in Hospitalized Older PatientsK23AG033763 · NIA · UNIVERSITY OF CHICAGO · PI ARORA, VINEET · 2009 to 2013
$762k
NCRR NIH HHS UL1 RR024999NIA NIH HHS 1 K24 AG031326-01NIA NIH HHS K23 AG033763NIA NIH HHS K24 AG031326NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

backgroundSleep-disordered breathing (SDB), also known as obstructive sleep apnea (OSA), has been increasingly recognized as a possible risk factor for adverse perioperative outcomes in non-bariatric surgeries. However, the impact of SDB on postoperative outcomes in patients undergoing bariatric surgery remains less clearly defined. We hypothesized that SDB would be independently associated with worse postoperative outcomes.

methodsData were obtained from the Nationwide Inpatient Sample database and included a total of 91,028 adult patients undergoing bariatric surgeries from 2004 to 2008. The primary outcomes were in-hospital death, total charges, and length of stay. There were two secondary outcomes of interest: respiratory and cardiac complications. Regression models were fitted to assess the independent association between SDB and the outcomes of interest.

resultsSDB was independently associated with decreased mortality (OR = 0.34, 95% CI = 0.23-0.50, p < 0.001), total charges (-$869, p < 0.001), and length of stay (-0.25 days, p < 0.001). SDB was independently associated with significantly increased odds ratio of emergent endotracheal intubation (OR = 4.35, 95% CI = 3.97-4.77, p < 0.001), noninvasive ventilation (OR = 14.12, 95% CI = 12.09-16.51, p < 0.001), and atrial fibrillation (OR = 1.25, 95% CI = 1.11-1.41, p < 0.001). Emergent intubation occurred significantly earlier in the postoperative course in patients with SDB. Although non-SDB patients had an overall lower risk of emergent intubation compared to SDB patients, their outcomes were significantly worse when they did get emergently intubated.

conclusionsIn this large nationally representative sample, despite the increased association of SDB/OSA with postoperative cardiopulmonary complications, the diagnosis of SDB/OSA was negatively, rather than positively, associated with in-hospital mortality and resource use.

Indexed as

Bariatric SurgeryHospital MortalityAdultDatabases, FactualEmergency TreatmentFemaleHealth ResourcesHumansInpatientsIntubation, IntratrachealLength of StayMaleObesity, MorbidOdds RatioRespiration, ArtificialRisk Assessment

Identifiers

PMID23690272
PMCPMC3791320
OpenAlexW2031842037

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.