ReviewCurrent hypertension reports2013
The role of CNS in salt-sensitive hypertension.
Review in Current hypertension reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed.
- Pilot analysis of protein profile alterations in plasma and aortic tissue of spontaneously hypertensive rats.Acta biochimica Polonica · 2026Article
- Review
- Induction of Neuroinflammation and Brain Oxidative Stress by Brain-Derived Extracellular Vesicles from Hypertensive Rats.Antioxidants (Basel, Switzerland) · 2024Article
- Review
- Central GαiFrontiers in endocrinology · 2022Review
- Biochemical interaction of salt sensitivity: a key player for the development of essential hypertension.Molecular and cellular biochemistry · 2021Review
- Review of the health benefits of habitual consumption of miso soup: focus on the effects on sympathetic nerve activity, blood pressure, and heart rate.Environmental health and preventive medicine · 2020Review
- Hypothalamic Paraventricular Nucleus GαiHypertension (Dallas, Tex. : 1979) · 2020Article
- Serum Metabolomics Study Based on LC-MS and Antihypertensive Effect ofEvidence-based complementary and alternative medicine : eCAM · 2018Article
- Erythrocyte Salt Sedimentation Assay Does Not Predict Response to Renal Denervation.Frontiers in medicine · 2018Article
- Impaired sodium-evoked paraventricular nucleus neuronal activation and blood pressure regulation in conscious Sprague-Dawley rats lacking central Gαi2 proteins.Acta physiologica (Oxford, England) · 2016Article
- The Role of CNS in the Effects of Salt on Blood Pressure.Current hypertension reports · 2016Review
- Gαi2-protein-mediated signal transduction: central nervous system molecular mechanism countering the development of sodium-dependent hypertension.Hypertension (Dallas, Tex. : 1979) · 2015Article
- Brain Gαi 2 -subunit proteins and the prevention of salt sensitive hypertension.Frontiers in physiology · 2015Review
- Systemic and renal oxidative stress in the pathogenesis of hypertension: modulation of long-term control of arterial blood pressure by resveratrol.Frontiers in physiology · 2014Review
- The Effects of the Habitual Consumption of Miso Soup on the Blood Pressure and Heart Rate of Japanese Adults: A Cross-sectional Study of a Health Examination.Internal medicine (Tokyo, Japan)Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of sympathetic nerve activity in hypertension is currently receiving increased attention, because catheter-based renal denervation was recently shown to reduce blood pressure safely in patients with treatment-resistant hypertension. The central nervous system, which regulates sympathetic nerve activity and blood pressure, is pivotal. Central sympathoexcitation has been shown to be deeply involved in the pathogenesis of salt-sensitive hypertension, although its precise mechanisms have not yet been fully elucidated due to their complexity. Recently, a role for brain oxidative stress in sympathoexcitation has been suggested in some hypertensive animal models. We have demonstrated that increased brain oxidative stress may elevate arterial pressure through central sympathoexcitation in salt-sensitive hypertension. Several factors other than oxidative stress have also been shown to play important roles in central sympathetic activation. In the future, strategies may be developed to elicit a sympathetic inhibition by modulating these factors to prevent and manage salt-sensitive hypertension.
Indexed as
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23689978What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.