Evidence map›Paper›PMID 23689533›Full record

SynthesisMolecular psychiatry2014

Childhood maltreatment and obesity: systematic review and meta-analysis.

A Danese, M Tan

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Molecular psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05490121 (Evaluating an Educational Intervention for Improving Residents' Recognition and Response to Child Maltreatment - A Mixed Method Acceptability and Feasibility Study With a Pilot Randomized Trial), which is not on this map. Cited by 368 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
368citing papers in PubMed, 15 pooled it
38.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05490121 nacompletednot on this mapstarted 2022, after this paper: background citation

Evaluating an Educational Intervention for Improving Residents' Recognition and Response to Child Maltreatment - A Mixed Method Acceptability and Feasibility Study With a Pilot Randomized Trial

TypeinterventionalSponsorMcMaster UniversityRan2022 to 2023Enrolled84ConditionsDomestic Violence, Child Maltreatment, Pediatric ALL, PsychiatryArmsViolence, Evidence, Guidance, Action Project (VEGA) Education Intervention
3 · Its place in the literature

Who cites it

368 citing papers in PubMed, 15 syntheses or guidelines pooled it, 702 citations in OpenAlex.

  1. Dimensions of early life adversity and cardiometabolic health in adulthood: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
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  3. A Systematic Review and Meta-Analytic Assessment of Unpredictability and Disordered Eating.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
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  6. Identifying Key Predictors of Mid-Childhood Obesity in a Population-Based Cohort Study: An Evidence Synthesis and Predictive Modeling Study.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
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  14. The association between adverse childhood experiences and childhood obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
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  16. Trial
  17. Parent-Child Interaction Therapy Supports Healthy Eating Behavior in Child Welfare-Involved Children.International journal of environmental research and public health · 2022
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  20. Article

308 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

A DaneseMRC Social, Genetic and Developmental Psychiatry (SGDP) Centre and Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King's College London, London, UK.
M TanMRC Social, Genetic and Developmental Psychiatry (SGDP) Centre and Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King's College London, London, UK.
King's College London · GB

Funding

Validating a minimally-invasive assay to study the genomic fingerprint of stressR21HL109396 · NHLBI · KING'S COLLEGE LONDON · PI DANESE, ANDREA, PLOMIN, ROBERT · 2011 to 2012
$293k
Medical Research Council G1002190Medical Research Council G9806489NHLBI NIH HHS R21HL109396
6 · The paper itself

Abstract

Obesity is a prevalent global-health problem associated with substantial morbidity, impairment and economic burden. Because most readily available forms of treatment are ineffective in the long term, it is essential to advance knowledge of obesity prevention by identifying potentially modifiable risk factors. Findings from experimental studies in non-human primates suggest that adverse childhood experiences may influence obesity risk. However, observations from human studies showed heterogeneous results. To address these inconsistencies, we performed Medline, PsycInfo and Embase searches till 1 August 2012 for articles examining the association between childhood maltreatment and obesity. We then conducted a meta-analysis of the identified studies and explored the effects of various possible sources of bias. A meta-analysis of 41 studies (190 285 participants) revealed that childhood maltreatment was associated with elevated risk of developing obesity over the life-course (odds ratio=1.36; 95% confidence interval=1.26-1.47). Results were not explained by publication bias or undue influence of individual studies. Overall, results were not significantly affected by the measures or definitions used for maltreatment or obesity, nor by confounding by childhood or adult socioeconomic status, current smoking, alcohol intake or physical activity. However, the association was not statistically significant in studies of children and adolescents, focusing on emotional neglect, or adjusting for current depression. Furthermore, the association was stronger in samples including more women and whites, but was not influenced by study quality. Child maltreatment is a potentially modifiable risk factor for obesity. Future research should clarify the mechanisms through which child maltreatment affects obesity risk and explore methods to remediate this effect.

Indexed as

Child AbuseAdolescentAdultChildChild, PreschoolEthnicityFemaleHumansMaleMiddle AgedObesityOdds RatioRegression AnalysisRisk FactorsSensitivity and SpecificitySex Factors

Identifiers

PMID23689533
OpenAlexW2026340830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.