ArticleThe American journal of the medical sciences2014
Predictors of long-term mortality after severe sepsis in the elderly.
Article in The American journal of the medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparison of Prognostic Accuracy of the quick Sepsis-Related Organ Failure Assessment between Short- & Long-term Mortality in Patients Presenting Outside of the Intensive Care Unit - A Systematic Review & Meta-analysis.Scientific reports · 2018Pooled it
- The role of increased body mass index in outcomes of sepsis: a systematic review and meta-analysis.BMC anesthesiology · 2017Pooled it
- Characteristics and outcomes of type 2 myocardial infarction in sepsis survivors.Frontiers in cardiovascular medicine · 2026Article
- Article
- A Retrospective Analysis of the Predictive Role of RDW, MPV, and MPV/PLT Values in 28-Day Mortality of Geriatric Sepsis Patients: Associations with APACHE II and SAPS II Scores.Medicina (Kaunas, Lithuania) · 2025Article
- Two-Year Mortality and Prognostic Factors in Sepsis: A Prospective Cohort Study of 714 Danish Emergency Department Patients.Clinical epidemiology · 2025Article
- Identification of Aging-Related Hub Genes (ATP11B, RBBP7, DOCK10, and NUP160) as Potential Biomarkers and Therapeutic Targets in Sepsis.Human mutation · 2025Article
- Social Determinants of Health and Risk-Adjusted Sepsis Mortality in the Nationwide Veterans Affairs Healthcare System.Journal of general internal medicine · 2024Observational
- Development and validation of a nomogram model for predicting 28-day mortality in patients with sepsis.Heliyon · 2024Article
- Impact of heart failure on outcomes in patients with sepsis: A systematic review and meta-analysis.World journal of clinical cases · 2023Article
- Serial evaluation of the serum lactate level with the SOFA score to predict mortality in patients with sepsis.Scientific reports · 2023Observational
- The Assessment of Social Determinants of Health in Postsepsis Mortality and Readmission: A Scoping Review.Critical care explorations · 2022Article
- Impact on 6-month outcomes of hospital trajectory in critically ill older patients: analysis of the ICE-CUB2 clinical trial.Annals of intensive care · 2022Article
- Occurrence and Risk Factors for New Dependency on Chronic Care, Respiratory Support, Dialysis and Mortality in the First Year After Sepsis.Frontiers in medicine · 2022Article
- Bacteria and Sepsis: Microbiome to the Rescue?Journal of clinical medicine · 2021Review
- Immune Cell Number, Phenotype, and Function in the Elderly with Sepsis.Aging and disease · 2021Review
- Fluid resuscitation and outcomes in heart failure patients with severe sepsis or septic shock: A retrospective case-control study.PloS one · 2021Article
- Long Non-Coding RNAs as Biomarkers and Therapeutic Targets in Sepsis.Frontiers in immunology · 2021Review
- Long-Term Survival Following Sepsis.Deutsches Arzteblatt international · 2020Article
- A three-year retrospective multi-center study on time to surgery and mortality for isolated geriatric hip fractures.Journal of clinical orthopaedics and trauma · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundMortality rates after severe sepsis are extremely high, and the main focus of most research is short-term mortality, which may not be associated with long-term outcomes. The purpose of this study was to examine long-term mortality after a severe sepsis and identify factors associated with this mortality.
methodsThe authors performed a population-based study using Veterans' Affairs administrative data of patients aged 65 years and older. The outcome of interest was mortality > 90 days following hospitalization. Our primary analyses were Cox proportional hazard models to examine specific risk factors for long-term mortality.
resultsThere were 2,727 patients that met the inclusion criteria. Overall mortality was 55%, and 1- and 2-year mortality rates were 31% and 43%, respectively. Factors significantly associated with long-term mortality included congestive heart failure, peripheral vascular disease, dementia, diabetes with complications and use of mechanical ventilation. Smoking cessation and cardiac medications were associated with decreased long-term mortality rates.
conclusionsThe authors identified several factors, including receipt of mechanical ventilation, which were significantly associated with increased long-term mortality for survivors of severe sepsis. This information will help clinicians discuss prognosis with patients and their families.
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