Evidence map›Paper›PMID 23688352›Full record

ArticleClinical and translational medicine2013

Regenerative medicine for the kidney: stem cell prospects & challenges.

Yue Li, Rebecca A Wingert

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Podocyte-Specific Sialylation-Deficient Mice Serve as a Model for Human FSGS.Journal of the American Society of Nephrology : JASN · 2019
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury.Journal of visualized experiments : JoVE · 2016
    Article
  15. Review
  16. Review
  17. Article
  18. Cell-based therapy for kidney disease.Korean journal of urology · 2015
    Review
  19. Article
  20. The lymph node as a new site for kidney organogenesis.Stem cells translational medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yue LiDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA. rwingert@nd.edu.
Rebecca A Wingert
University of Notre Dame · US

Funding

Identification of Kidney Regeneration Mechanisms Using the ZebrafishDP2OD008470 · OD · UNIVERSITY OF NOTRE DAME · PI WINGERT, REBECCA ANN · 2011 to 2011
$2.3M
Genetic Analysis of Pathways Controlling Nephron Segmentation Using the ZebrafishK01DK083512 · NIDDK · UNIVERSITY OF NOTRE DAME · PI WINGERT, REBECCA ANN · 2009 to 2013
$644k
NIDDK NIH HHS K01 DK083512NIH HHS DP2 OD008470
6 · The paper itself

Abstract

The kidney has key roles in maintaining human health. There is an escalating medical crisis in nephrology as growing numbers of patients suffer from kidney diseases that culminate in organ failure. While dialysis and transplantation provide life-saving treatments, these therapies are rife with limitations and place significant burdens on patients and healthcare systems. It has become imperative to find alternative ways to treat existing kidney conditions and preemptive means to stave off renal dysfunction. The creation of innovative medical approaches that utilize stem cells has received growing research attention. In this review, we discuss the regenerative and maladaptive cellular responses that occur during acute and chronic kidney disease, the emerging evidence about renal stem cells, and some of the issues that lie ahead in bridging the gap between basic stem cell biology and regenerative medicine for the kidney.

Identifiers

PMID23688352
PMCPMC3665577
OpenAlexW2099065391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.