ArticleChemical communications (Cambridge, England)2013
NanoSIMS multi-element imaging reveals internalisation and nucleolar targeting for a highly-charged polynuclear platinum compound.
Article in Chemical communications (Cambridge, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
- A trackable trinuclear platinum complex for breast cancer treatment.Nucleic acids research · 2025Article
- Modern Bioimaging Techniques for Elemental Tissue Analysis: Key Parameters, Challenges and Medical Impact.Molecules (Basel, Switzerland) · 2025Review
- Albumin-targeting of an oxaliplatin-releasing platinum(iv) prodrug results in pronounced anticancer activity due to endocytotic drug uptakeChemical science · 2021Article
- Nano-scale imaging of dual stable isotope labeled oxaliplatin in human colon cancer cells reveals the nucleolus as a putative node for therapeutic effect.Nanoscale advances · 2021Article
- Subcellular Mass Spectrometry Imaging and Absolute Quantitative Analysis across Organelles.ACS nano · 2020Article
- Deciphering Metabolic Heterogeneity by Single-Cell Analysis.Analytical chemistry · 2019Article
- Boron-Containing Probes for Non-optical High-Resolution Imaging of Biological Samples.Angewandte Chemie (International ed. in English) · 2019Article
- Tissue Imaging by Mass Spectrometry: A Practical Guide for the Medicinal Chemist.ACS medicinal chemistry letters · 2019Article
- Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA.Nature nanotechnology · 2018Article
- Tumor Retention of Enzyme-Responsive Pt(II) Drug-Loaded Nanoparticles Imaged by Nanoscale Secondary Ion Mass Spectrometry and Fluorescence Microscopy.ACS central science · 2018Article
- Subcellular Targeting of Theranostic Radionuclides.Frontiers in pharmacology · 2018Review
- Visualization of metallodrugs in single cells by secondary ion mass spectrometry imaging.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2017Review
- Synchrotron X-Ray Fluorescence Nanoprobe Reveals Target Sites for Organo-Osmium Complex in Human Ovarian Cancer Cells.Chemistry (Weinheim an der Bergstrasse, Germany) · 2017Article
- Antiangiogenic platinum through glycan targeting.Chemical science · 2017Article
- Multi-scale imaging of anticancer platinum(iv) compounds in murine tumor and kidney.Chemical science · 2016Article
- Cellular Delivery of Nanoparticles Revealed with Combined Optical and Isotopic Nanoscopy.ACS nano · 2016Article
- Review
- Evaluation of fluorophore-tethered platinum complexes to monitor the fate of cisplatin analogs.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2015Article
- Solution studies on DNA interactions of substitution-inert platinum complexes mediated via the phosphate clamp.Dalton transactions (Cambridge, England : 2003) · 2015Article
- Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction.Molecular pharmaceutics · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Simultaneous multi-element imaging using NanoSIMS (nano-scale secondary ion mass spectrometry), exploiting the novel combination of (195)Pt and (15)N in platinum-am(m)ine antitumour drugs, provides information on the internalisation and subcellular localisation of both metal and ligands, and allows identification of ligand exchange.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.