Evidence map›Paper›PMID 23687579›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2012

Nevirapine-Resistant HIV-1 DNA in Breast Milk After Single-Dose Nevirapine With or Without Zidovudine for Prevention of Mother-to-Child Transmission.

Soren Gantt, Rachel Payant, Jacquelyn Carlsson, Mark A Micek, Ana Judith Blanco, Ingrid A Beck, Laurinda Matunha, Pablo Montoya, Eduardo Matediana, Stephen Gloyd and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Soren GanttDepartments of Pediatrics Seattle Children's Hospital Research Institute, Center for Childhood Infections.
Rachel PayantSeattle Children's Hospital Research Institute, Center for Childhood Infections.
Jacquelyn CarlssonSeattle Children's Hospital Research Institute, Center for Childhood Infections.
Mark A MicekGlobal Health, and Health Alliance International, Seattle, Washington.
Ana Judith BlancoGlobal Health, and Health Alliance International, Seattle, Washington.
Ingrid A BeckSeattle Children's Hospital Research Institute, Center for Childhood Infections.
Laurinda MatunhaHealth Alliance International, Seattle, Washington.
Pablo MontoyaGlobal Health, and Health Alliance International, Seattle, Washington.
Eduardo MatedianaMozambique Ministry of Health, Maputo.
Stephen GloydGlobal Health, and Health Alliance International, Seattle, Washington.
Lisa M FrenkelDepartments of Pediatrics Laboratory Medicine, University of Washington Seattle Children's Hospital Research Institute, Center for Childhood Infections.
Seattle Children's Hospital · USCenter for Global Health · USHealth Alliance International · USMinistry of Health · MZUniversity of Washington · US

Funding

VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
NCCIH Supplement to NCATS/CTSA Program for KL2 Scholars - M. SoddersKL2TR002317 · NCATS · UNIVERSITY OF WASHINGTON · PI Christy Michelle McKinney · 2017 to 2026
$14.5M
Institute for Translational Health Science (KL2)KL2RR025015 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$9.3M
ACADEMIC PEDIATRIC INFECTIOUS DISEASET32HD007233 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI KEVIN B URDAHL · 1985 to 2026
$6.7M
Reservoirs of drug-resistant HIV-1R01AI058723 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI FRENKEL, LISA M · 2005 to 2009
$2.0M
NCATS NIH HHS KL2 TR002317NCRR NIH HHS KL2 RR025015NIAID NIH HHS R01 AI058723NIAID NIH HHS T32 AI007140NICHD NIH HHS T32 HD007233
6 · The paper itself

Abstract

Among 30 human immunodeficiency virus type 1 (HIV-1)-infected women who received single-dose nevirapine (NVP), 17 (57%) had NVP-resistant HIV-1 detected in breast milk. NVP resistance in breast milk persisted for at least 8 months postpartum and was apparently transmitted to at least 1 infant. NVP resistance was detected less often in women who also received zidovudine.

Identifiers

PMID23687579
PMCPMC3656540
OpenAlexW2102960985

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.