ReviewJournal of the Pediatric Infectious Diseases Society2012
Clostridium difficile Infection in Children: Current State and Unanswered Questions.
Review in Journal of the Pediatric Infectious Diseases Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 70 citations in OpenAlex.
- Evaluation of the prevalence of Aeromonas spp., Campylobacter spp., and Clostridioides difficile in immunocompromised children with diarrhea.BMC infectious diseases · 2024Article
- Clostridioides difficile Infections: Prevention and Treatment Strategies.Advances in experimental medicine and biology · 2024Review
- Pediatric diarrhea patients living in urban areas have a higher incidence of Clostridioides difficile infection.PLOS global public health · 2023Article
- Stool Toxin Concentration Does Not Distinguish Clostridioides difficile Infection from Colonization in Children Less Than 3 Years of Age.Journal of the Pediatric Infectious Diseases Society · 2022Article
- Comparison of clinical severity, genotype and toxin gene expression of binary toxin-producingAccess microbiology · 2022Article
- Clostridium difficile Colonization Before and After Hospitalization in Children.Turkish archives of pediatrics · 2021Article
- Fidaxomicin for the treatment ofFuture microbiology · 2020Article
- Natural Clostridioides difficile Toxin Immunization in Colonized Infants.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- South African Society of Clinical MicrobiologySouthern African journal of infectious diseases · 2020Article
- Healthcare provider diagnostic testing practices for identification of Clostridioides (Clostridium) difficile in children: an Emerging Infections Network survey.Infection control and hospital epidemiology · 2019Article
- Gut microbiota features associated with Clostridioides difficile colonization in puppies.PloS one · 2019Article
- Article
- Clostridium difficile Whole Genome Sequencing Reveals Limited Transmission Among Symptomatic Children: A Single-Center Analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Healthcare-associated Clostridium difficile infection: role of correct hand hygiene in cross-infection control.Journal of preventive medicine and hygiene · 2018Article
- Community-acquired Clostridium difficile infection in Serbian pediatric population.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018Article
- Clostridium difficile cure with fecal microbiota transplantation in a child with Pompe disease: a case report.Journal of medical case reports · 2018Article
- Impact of a Healthcare Provider Educational Intervention on Frequency of Clostridium difficile Polymerase Chain Reaction Testing in Children: A Segmented Regression Analysis.Journal of the Pediatric Infectious Diseases Society · 2017Article
- Potential causative agents of acute gastroenteritis in households with preschool children: prevalence, risk factors, clinical relevance and household transmission.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016Article
- Differences in the Molecular Epidemiology and Antibiotic Susceptibility of Clostridium difficile Isolates in Pediatric and Adult Patients.Antimicrobial agents and chemotherapy · 2016Article
- Risk Factors for Community-associated Clostridium difficile-associated Diarrhea in Children.The Pediatric infectious disease journal · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The incidence of Clostridium difficile infection (CDI) in children has increased over the past decade. In recent years, new and intriguing data on pediatric CDI have emerged. Community-onset infections are increasingly recognized, even in children who have not previously received antibiotics. A hypervirulent strain is responsible for up to 20% of pediatric CDI cases. Unique risk factors for CDI in children have been identified. Advances in diagnostic testing strategies, including the use of nucleic acid amplification tests, have raised new questions about the optimal approach to diagnosing CDI in children. Novel therapeutic options are available for adult patients with CDI, raising questions about the use of these agents in children. Updated recommendations about infection prevention and control measures are now available. We summarize these recent developments in pediatric CDI in this review and also highlight remaining knowledge gaps that should be addressed in future research efforts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.