ArticleJournal of bacteriology2013
Role of polyphosphate in thermophilic Synechococcus sp. from microbial mats.
Article in Journal of bacteriology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 41 citations in OpenAlex.
- ModifiedMicroorganisms · 2026Article
- Article
- Polyphosphate Attenuates Oxidative Stress to Support Temperature Adaptability in Hot Spring Cyanobacteria.Plants (Basel, Switzerland) · 2026Article
- Polyphosphate acts as an architectural regulator of carbon fixation and nucleoid structure in cyanobacteria.bioRxiv : the preprint server for biology · 2026Article
- High-Purity Isolation of Polyphosphate-Rich Stabilisomes Defines Their Conserved Chemical Architecture in Thermophilic Cyanobacteria.Plants (Basel, Switzerland) · 2026Article
- A summer in the greater Paris: trophic status of peri-urban lakes shapes prokaryotic community structure and functional potential.Environmental microbiome · 2025Article
- Getting Grip on Phosphorus: Potential of Microalgae as a Vehicle for Sustainable Usage of This Macronutrient.Plants (Basel, Switzerland) · 2024Review
- Polyphosphate-kinase-1 dependent polyphosphate hyperaccumulation for acclimation to nutrient loss in the cyanobacterium,Frontiers in plant science · 2024Article
- Polyphosphate kinase deletion increases laboratory productivity in cyanobacteria.Frontiers in plant science · 2024Article
- Pleiotropic effects of PipX, PipY, or RelQ overexpression on growth, cell size, photosynthesis, and polyphosphate accumulation in the cyanobacteriumFrontiers in microbiology · 2023Article
- Schindler's legacy: from eutrophic lakes to the phosphorus utilization strategies of cyanobacteria.FEMS microbiology reviews · 2022Review
- Patterning of the Autotrophic, Mixotrophic, and Heterotrophic Proteomes of Oxygen-Evolving CyanobacteriumFrontiers in microbiology · 2022Article
- Metabolic engineering of phosphite metabolism inBiotechnology for biofuels · 2020Article
- Polyphosphate: A Multifunctional Metabolite in Cyanobacteria and Algae.Frontiers in plant science · 2020Review
- Biogenic Polyphosphate Nanoparticles from a Marine CyanobacteriumMarine drugs · 2018Article
- Overproduction, purification, and characterization of nanosized polyphosphate bodies from Synechococcus sp. PCC 7002.Microbial cell factories · 2018Article
- Polyphosphate: popping up from oblivion.Current genetics · 2017Review
- Spontaneous non-canonical assembly of CcmK hexameric components from β-carboxysome shells of cyanobacteria.PloS one · 2017Article
- Critical function of a Chlamydomonas reinhardtii putative polyphosphate polymerase subunit during nutrient deprivation.The Plant cell · 2014Article
- Intracellular Ca-carbonate biomineralization is widespread in cyanobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synechococcus OS-B', a thermophilic unicellular cyanobacterium, recently isolated from the microbial mats in Octopus Spring (Yellowstone National Park), induces a suite of genes, including phosphatases and transporters, in response to phosphorus (P) starvation. Here we describe two different approaches to examine the ability of Synechococcus OS-B' to synthesize and break down polyphosphate (poly P), a key storage compound in many prokaryotes. First, we developed a transformation protocol to create mutants in the polyphosphate kinase (ppk), the major enzyme responsible for the synthesis of poly P. The ppk mutant exhibited a pleiotropic phenotype with defects in poly P accumulation, aberrant levels of Pho regulon transcripts, growth defects, and changes in cell size and exopolysaccharide levels, among others. Second, we measured transcripts of ppk and ppx (encoding the polyphosphatase) directly from mat samples and found that the levels varied dramatically over a diel cycle. We also used Western blot analysis to quantify levels of PPK and PPX and found that these enzymes differentially accumulated during the diel cycle. Levels of polyphosphate kinase peaked at night, while polyphosphatase levels were highest during the early morning hours. We hypothesize that the opposing activities of these two enzymes allow cells to store and utilize poly P to optimize growth over a diel cycle.
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Registered trials
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