Evidence map›Paper›PMID 23686418›Full record

ArticleThe Laryngoscope2013

The effect of geniglossal advancement on airway flow using a computational flow dynamics model.

Aaron Fletcher, Jiwoong Choi, Maged Awadalla, Andrea E Potash, Tanner J Wallen, Steven Fletcher, Eugene H Chang

Open access · greenAbstract readComparative Study
In one paragraph

Article in The Laryngoscope, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Aaron FletcherDepartment of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, U.S.A.
Jiwoong Choi
Maged Awadalla
Andrea E Potash
Tanner J Wallen
Steven Fletcher
Eugene H Chang
University of Iowa · US

Funding

University of Iowa Clinical and Translational Science Program (KL2)KL2RR024980 · NCRR · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2007 to 2011
$4.6M
Investigation of CFTR on sinus and craniofacial development in a CF porcine modelK08DE021413 · NIDCR · UNIVERSITY OF IOWA · PI CHANG, EUGENE H · 2011 to 2015
$625k
NCRR NIH HHS KL2 RR024980NCRR NIH HHS KL2RR024980NIDCR NIH HHS DE021413-01A1NIDCR NIH HHS K08 DE021413
6 · The paper itself

Abstract

objectives/hypothesisObstructive sleep apnea (OSA) is a sleep disorder caused by partial or complete collapse of the pharyngeal airway. Genioglossal advancement (GGA) is a well-tolerated surgical procedure intended to address hypopharyngeal collapse, yet there are few studies that monitor changes in airflow dynamics at this site. Computation fluid dynamics (CFD) utilizes airflow simulation to predict changes in airflow after anatomic manipulation. STUDY

designWe investigated the change in volume and airflow dynamics of the pharyngeal airway after GGA in a cadaveric model.

methodsWe performed serial GGA from 1 mm (control) to 3, 7, and 9 mm on a lightly preserved cadaver. After each intervention, we performed high-resolution computed tomography scans, reconstructed the pharyngeal airway, and quantified airspace volume and CFD analysis with both laminar and large eddy simulation models.

resultsAirway volume increased with linear GGA. In both CFD simulation models, velocity increased and pressure decreased after 9-mm advancement secondary to increased airway diameter and less abrupt changes in airway geometry.

conclusionsThese results suggest that GGA may be effective in increasing airway volume and flow to address hypopharyngeal obstruction in OSA.

Indexed as

Computer SimulationAirway ResistanceCadaverHumansHydrodynamicsImaging, Three-DimensionalPharynxSleep Apnea, ObstructiveTomography, X-Ray Computedcomputational flow dynamicsgenioglossal advancementObstructive sleep apnea

Identifiers

PMID23686418
PMCPMC3783525
OpenAlexW2116396179

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.