ArticleJournal of cachexia, sarcopenia and muscle2013
Development and relative validity of a new field instrument for detection of geriatric cachexia: preliminary analysis in hip fracture patients.
Article in Journal of cachexia, sarcopenia and muscle, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Effect of total knee replacement on skeletal muscle mass measurements using dual energy X-ray absorptiometry.Scientific reports · 2023Article
- Nutritional Status and Nutritional Treatment Are Related to Outcomes and Mortality in Older Adults with Hip Fracture.Nutrients · 2018Review
- Nutritional status in the elderly: misbeliefs, misconceptions and the real world.Wiener klinische Wochenschrift · 2016Article
- Measuring Appetite with the Simplified Nutritional Appetite Questionnaire Identifies Hospitalised Older People at Risk of Worse Health Outcomes.The journal of nutrition, health & aging · 2016Article
- Article
- Loss of muscle mass: current developments in cachexia and sarcopenia focused on biomarkers and treatment.Journal of cachexia, sarcopenia and muscle · 2015Review
- Muscle wasting in ageing and chronic illness.ESC heart failure · 2015Review
- Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology-update 2014.Journal of cachexia, sarcopenia and muscle · 2014Article
- Rehabilitation nutrition for sarcopenia with disability: a combination of both rehabilitation and nutrition care management.Journal of cachexia, sarcopenia and muscle · 2014Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGeriatric cachexia is distinct from other age-related muscle wasting syndromes; however, detection and therefore treatment is challenging without the availability of valid instruments suitable for application in the clinical setting. This study assessed the sensitivity and specificity of a newly developed screening instrument utilising portable assessments against previously defined and commonly accepted diagnostic criteria for detection of geriatric cachexia.
methodsCross-sectional analyses from 71 older adults' post-surgical fixation for hip fracture were performed. The diagnostic criteria required measures of appendicular skeletal muscle index derived from dual-energy X-ray absorptiometry and anorexia assessed by ≤70 % of estimated energy requirements. These assessments were replaced with mid-upper arm muscle circumference and the Simplified Nutritional Appetite Questionnaire, respectively, to create a field instrument suitable for screening geriatric cachexia. Sensitivity, specificity and positive and negative predictive values were calculated.
resultsThe current diagnostic algorithm identified few patients as cachectic (4/71; 5.6 %). The sensitivity and specificity of the geriatric cachexia screening tool was 75 and 97 %, respectively. The screening tool had a positive predictive value of 60 % and a negative predictive value of 99 %.
conclusionsGiven the unexpected prevalence of cachexia in such a vulnerable group, these results may suggest problems in operationalising of the consensus definition and diagnostic criteria. Although the application of a newly developed screening tool using portable field measures looks promising, the authors recommend additional research to identify the prevalence of geriatric cachexia, which captures all diagnostic criteria from the consensus definition. Future investigation may then be positioned to explore the predictive validity of screening tools using portable field measures, which potentially achieve higher sensitivity.
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Registered trials
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