Evidence map›Paper›PMID 23686321›Full record

Observational studyHeart and vessels2014

Contrast echocardiography for the diagnosis of left ventricular thrombus in anterior myocardial infarction.

Hiroshi Wada, Takanori Yasu, Kenichi Sakakura, Yuki Hayakawa, Takeshi Ishida, Nobuhiko Kobayashi, Norifumi Kubo, Junya Ako, Shin-ichi Momomura

Abstract readComparative StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Heart and vessels, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Direct Oral Anticoagulants Versus Vitamin K Antagonists in the Treatment of Left Ventricular Thrombi.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2022
    Article
  4. Observational
  5. Management of left ventricular thrombus: a narrative review.Annals of translational medicine · 2021
    Review
  6. Review
  7. Challenges in management of left ventricular thrombus.Therapeutic advances in cardiovascular disease · 2017
    Review
  8. Postoperative Assessment of Myocardial Function and Microcirculation in Patients with Acute Coronary Syndrome by Myocardial Contrast Echocardiography.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hiroshi WadaFirst Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma, Omiya, Saitama, Saitama, 330-8503, Japan.
Takanori Yasu
Kenichi Sakakura
Yuki Hayakawa
Takeshi Ishida
Nobuhiko Kobayashi
Norifumi Kubo
Junya Ako
Shin-ichi Momomura
Jichi Medical University · JPJichi Medical University Saitama Medical Center · JPDokkyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although detecting left ventricular thrombus in anterior myocardial infarction is important for the prevention of embolic events, imaging of apical thrombus is often difficult using conventional echocardiography. We examined whether contrast echocardiography improves sensitivity and specificity in detecting thrombus in the left ventricle in comparison with conventional echocardiography alone in patients with anterior myocardial infarction. Participants in this single-center prospective study comprised 392 patients with anterior myocardial infarction admitted between 2000 and 2006. After conventional echocardiography, all patients underwent contrast echocardiography (left ventricular opacification and myocardial contrast echocardiography) during intravenous drip infusion of contrast media at rest. Left ventricular thrombus was diagnosed based on left ventriculography or multidetector-row computed tomography (MDCT). Mural left ventricular thrombus was confirmed by left ventriculography and/or MDCT in 32 of 393 patients (8 %). Sensitivity and specificity of conventional echocardiography alone were 88 % and 96 %, respectively, compared with 100 % each with contrast echocardiography. Among the 32 patients with left ventricular thrombus, 25 patients (78 %) showed no perfusion in the anterior wall on myocardial contrast echocardiography, even with a four-beat interval. In conclusion, contrast echocardiography offers a clinically feasible and useful method for noninvasively evaluating left ventricular thrombus in anterior myocardial infarction.

Indexed as

Contrast MediaPolysaccharidesAgedAnterior Wall Myocardial InfarctionFeasibility StudiesFemaleHeart DiseasesHumansInfusions, IntravenousJapanMaleMultidetector Computed TomographyPredictive Value of TestsProspective StudiesThrombosisUltrasonographyContrast MediaPolysaccharidesSHU 508

Identifiers

PMID23686321
OpenAlexW1997043041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.