ArticleOccupational and environmental medicine2013
Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: the Multiethnic Study of Atherosclerosis (MESA).
Article in Occupational and environmental medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Relationship Between Occupational Characteristics and Telomere Length in Female Nurses Aged 20-39 Years: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Structural and social determinants of health: The multi-ethnic study of atherosclerosis.PloS one · 2024Article
- Work-Related Psychosocial Factors and Global Cognitive Function: Are Telomere Length and Low-Grade Inflammation Potential Mediators of This Association?International journal of environmental research and public health · 2023Article
- The Network Structure of Occupations: Fragmentation, Differentiation, and Contagion.AJS; American journal of sociology · 2022Article
- Learning on the job, the use of selection, optimization, and compensation strategies, and their association with telomere length as an indicator of biological aging.International archives of occupational and environmental health · 2019Article
- A scoping systematic review of social stressors and various measures of telomere length across the life course.Ageing research reviews · 2018Article
- Foods, Dietary Patterns and Occupational Class and Leukocyte Telomere Length in the Male Population.American journal of men's health · 2018Article
- Article
- Telomeres, Aging and Exercise: Guilty by Association?International journal of molecular sciences · 2017Review
- Physical activity and telomere length: Impact of aging and potential mechanisms of action.Oncotarget · 2017Review
- Maternal occupational physical activity and risk for orofacial clefts.American journal of industrial medicine · 2017Article
- Relating Older Workers' Injuries to the Mismatch Between Physical Ability and Job Demands.Journal of occupational and environmental medicine · 2017Article
- Lifespan adversity and later adulthood telomere length in the nationally representative US Health and Retirement Study.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Telomere Length Maintenance and Cardio-Metabolic Disease Prevention Through Exercise Training.Sports medicine (Auckland, N.Z.) · 2016Review
- A Path Model of Job Stress Using Thai Job Content Questionnaire (Thai-JCQ) among Thai Immigrant Employees at the Central Region of Thailand.Iranian journal of public health · 2016Article
- Data linkage between the National Birth Defects Prevention Study and the Occupational Information Network (O*NET) to assess workplace physical activity, sedentary behaviors, and emotional stressors during pregnancy.American journal of industrial medicine · 2016Article
- Occupational characteristics and the progression of carotid artery intima-media thickness and plaque over 9 years: the Multi-Ethnic Study of Atherosclerosis (MESA).Occupational and environmental medicine · 2015Article
- The public health exposome: a population-based, exposure science approach to health disparities research.International journal of environmental research and public health · 2014Article
- Work-related premature ageing: old concept but emerging stakes.Occupational and environmental medicine · 2013Article
- Observational
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveTelomere length has been proposed as a biomarker of cell senescence, which is associated with a wide array of adverse health outcomes. While work is a major determinant of health, few studies have investigated the association of telomere length with various dimensions of occupation. Accelerated cellular aging could be a common pathway linking occupational exposure to several health outcomes.
methodsLeukocyte telomere length was assessed using quantitative PCR in a community-based sample of 981 individuals (age: 45-84 years). Questionnaires were used to collect information on current employment status, current or main occupation before retirement and job strain. The Occupational Resource Network (O*NET) database was linked to the questionnaire data to create five exposure measures: physical activity on the job, physical hazard exposure, interpersonal stressors, job control and job demands. Linear regression was used to estimate associations of occupational characteristics with telomere lengths after adjustment for age, sex, race, socioeconomic position and several behavioural risk factors.
resultsThere were no mean differences in telomere lengths across current employment status, occupational category, job strain categories or levels of most O*NET exposure measures. There was also no evidence that being in lower status occupational categories or being exposed to higher levels of adverse physical or psychosocial exposures accelerated the association between age and telomere shortening.
conclusionsCellular aging as reflected by shorter telomeres does not appear to be an important pathway linking occupation to various health outcomes.
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Registered trials
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