Evidence map›Paper›PMID 23686020›Full record

SynthesisSchizophrenia bulletin2014

A meta-analysis of mentalizing impairments in adults with schizophrenia and autism spectrum disorder.

Yu Sun Chung, Deanna Barch, Michael Strube

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Schizophrenia bulletin, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 13 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Autism spectrum disorder and schizophrenia: An updated conceptual review.Autism research : official journal of the International Society for Autism Research · 2022
    Pooled it
  8. Pooled it
  9. A Systematic Review of the Current Measures of Theory of Mind in Adults with Schizophrenia.International journal of environmental research and public health · 2021
    Pooled it
  10. Pooled it
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  14. Trial
  15. Neural and behavioral effects of oxytocin administration during theory of mind in schizophrenia and controls: a randomized control trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019
    Trial
  16. Cognitive enhancement therapy for adult autism spectrum disorder: Results of an 18-month randomized clinical trial.Autism research : official journal of the International Society for Autism Research · 2018
    Trial
  17. Trial
  18. Article
  19. The Network Model of Mentalization, Social Vulnerability, and the Self in Autism: A Comparison With Neurotypical Adults.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  20. Article

52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yu Sun Chung*To whom correspondence should be addressed; tel: 314-935-6260, fax: 314-935-8790, e-mail: yschung@wustl.edu.
Deanna Barch
Michael Strube

Funding

Schizophrenia, Prefrontal Cortex, and Emotion RegulationR01MH066031 · NIMH · WASHINGTON UNIVERSITY · PI BARCH, DEANNA · 2004 to 2014
$4.1M
NIMH NIH HHS R01 MH066031
6 · The paper itself

Abstract

Mentalizing has been examined both in autism spectrum disorder (ASD) and schizophrenia (SCZ) primarily by either cognitive-linguistic (referred to as verbal) or emotion recognition from eyes (referred to as visual) mentalizing tasks. Each type of task is thought to measure different aspects of mentalizing. Differences in clinical features and developmental courses of each disorder may predict distinct patterns of mentalizing performance across dis orders on each type of task. To test this, a meta-analysis was conducted using 37 studies that assessed mentalizing either verbally or visually in adults with SCZ or ASD. We found that the estimated effect sizes of impairments in verbal and visual mentalizing tasks for both clinical groups were statistically large and at a similar level (overall Hedges' g = 0.73-1.05). For each disorder, adults with SCZ showed a trend towards larger impairments on verbal (overall Hedges' g = 0.99) than on visual mentalizing task (overall Hedges' g = 0.73; Qbet = 3.45, p =.06, df =1). Adults with ASD did not show different levels of impairment on the verbal versus visual tasks (Qbet = 0.08, p =.78, df =1). These results suggest that both clinical groups share, at least in part, some common cognitive processing deficits associated with mentalizing impairments.

Indexed as

SchizophreniaSchizophrenic PsychologySocial PerceptionTheory of MindAdultChild Development Disorders, PervasiveCognition DisordersEmotionsFacial ExpressionHumansPattern Recognition, VisualRegression Analysisautism/social cognitionmentalizingschizophrenia

Identifiers

PMID23686020
PMCPMC3984506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.