Evidence map›Paper›PMID 23685327›Full record

ArticleAddictive behaviors2013

Prospective effects of adolescent indicators of behavioral disinhibition on DSM-IV alcohol, tobacco, and illicit drug dependence in young adulthood.

Rohan H C Palmer, Valerie S Knopik, Soo Hyun Rhee, Christian J Hopfer, Robin C Corley, Susan E Young, Michael C Stallings, John K Hewitt

Abstract readTwin Study
In one paragraph

Article in Addictive behaviors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. The Role of A Priori-Identified Addiction and Smoking Gene Sets in Smoking Behaviors.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Gender Differences in Relations among Perceived Family Characteristics and Risky Health Behaviors in Urban Adolescents.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2017
    Article
  18. Childhood attention-deficit/hyperactivity disorder symptoms and the development of adolescent alcohol problems: A prospective, population-based study of Swedish twins.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rohan H C PalmerDivision of Behavioral Genetics, Rhode Island Hospital, RI, USA. Rohan_Palmer@Brown.edu
Valerie S Knopik
Soo Hyun Rhee
Christian J Hopfer
Robin C Corley
Susan E Young
Michael C Stallings
John K Hewitt
University of Colorado Boulder · USRhode Island Hospital · USUniversity of Colorado Denver · US

Funding

Twin StudyP60DA011015 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HEWITT, JOHN K. · 1997 to 2013
$22.5M
RESEARCH TRAINING IN CHILD MENTAL HEALTHT32MH019927 · NIMH · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI Kristen G Benito, Anthony Spirito · 1994 to 2026
$7.8M
Neural Substrates of Executive Function: An fMRI Twin StudyR01MH063207 · NIMH · UNIVERSITY OF COLORADO AT BOULDER · PI FRIEDMAN, NAOMI P. · 2001 to 2018
$6.5M
DETERMINANTS OF BEHAVIORAL DEVELOPMENT IN CHILDRENR01HD010333 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI WADSWORTH, SALLY J · 1985 to 2010
$3.0M
Genetics of Adolescent Antisocial Drug DependenceR01DA021913 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HOPFER, CHRISTIAN J · 2008 to 2013
$2.9M
Prenatal tobacco exposure: effects on neuropsychological outcomes and ADHDR01DA023134 · NIDA · RHODE ISLAND HOSPITAL · PI KNOPIK, VALERIE S · 2008 to 2013
$2.7M
Systems Genetics of Alcoholism: Network-based Approaches for Genetics AssociationK01AA021113 · NIAAA · RHODE ISLAND HOSPITAL · PI PALMER, ROHAN HUGH CRAIG · 2012 to 2016
$838k
Executive Functions and Self-Regulation: A Twin StudyR56MH063207 · NIMH · UNIVERSITY OF COLORADO · PI HEWITT, JOHN K. · 2007 to 2007
$490k
NIAAA NIH HHS AA021113NIAAA NIH HHS K01 AA021113NICHD NIH HHS HD010333NICHD NIH HHS R01 HD010333NIDA NIH HHS DA011015NIDA NIH HHS DA021913NIDA NIH HHS DA023134NIDA NIH HHS L30 DA032090NIDA NIH HHS P60 DA011015NIDA NIH HHS R01 DA021913NIDA NIH HHS R01 DA023134NIMH NIH HHS MH019927NIMH NIH HHS MH063207NIMH NIH HHS R01 MH063207NIMH NIH HHS R56 MH063207NIMH NIH HHS T32 MH019927
6 · The paper itself

Abstract

objectiveTo identify robust predictors of drug dependence.

methodsThis longitudinal study included 2361 male and female twins from an ongoing longitudinal study at the Center for Antisocial Drug Dependence (CADD) at the University of Colorado Boulder and Denver campuses. Twins were recruited for the CADD project while they were between the ages of 12 and 18. Participants in the current study were on average approximately 15years of age during the first wave of assessment and approximately 20years of age at the second wave of assessment. The average time between assessments was five years. A structured interview was administered at each assessment to determine patterns of substance use and Diagnostic and Statistical Manual of Mental Disorders (DSM-IV; Fourth Edition) attention deficit hyperactivity disorder (ADHD), conduct disorder (CD), and drug dependence symptoms. Cloninger's Tridimensional Personality Questionnaire was also used to assess novelty seeking tendencies (NS). At the second wave of assessment, DSM-IV dependence symptoms were reassessed using the same interview. Path analyses were used to examine direct and indirect mechanisms linking psychopathology and drug outcomes.

resultsAdolescent substance use, CD, and NS predicted young adult substance dependence, whereas the predictive effects of ADHD were few and inconsistent. Furthermore, CD and NS effects were partially mediated by adolescent substance use.

conclusionsAdolescent conduct problems, novelty seeking, and drug use are important indices of future drug problems. The strongest predictor was novelty seeking.

Indexed as

Exploratory BehaviorModels, TheoreticalAdolescentAdolescent BehaviorAttention Deficit and Disruptive Behavior DisordersColoradoComorbidityDiagnostic and Statistical Manual of Mental DisordersFemaleHumansInterview, PsychologicalMalePersonality AssessmentProspective StudiesRisk FactorsSmoking

Identifiers

PMID23685327
PMCPMC3681900
OpenAlexW2051808575

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.