Evidence map›Paper›PMID 23685069›Full record

ReviewTrends in microbiology2013

The emerging world of the fungal microbiome.

Gary B Huffnagle, Mairi C Noverr

Open access · greenAbstract readReview
In one paragraph

Review in Trends in microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 299 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
299citing papers in PubMed, 1 pooled it
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

299 citing papers in PubMed, 1 synthesis or guideline pooled it, 571 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Review of the Microbial Spectrum of Mixed Respiratory Fungal Infections.Journal of epidemiology and global health · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Importance of human microbiome: an update.Frontiers in microbiomes · 2026
    Review
  13. Review
  14. Article
  15. Commensal colonization ofMicrobiology spectrum · 2025
    Article
  16. Article
  17. Review
  18. Mycobiome: an underexplored kingdom in cancer.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  19. Article
  20. Article

239 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gary B HuffnagleDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. ghuff@umich.edu
Mairi C Noverr
Louisiana State University Health Sciences Center New Orleans · USMichigan Medicine · US

Funding

University of Michigan Center for Gastrointestinal ResearchP30DK034933 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OWYANG, CHUNG · 1986 to 2021
$22.5M
The Interplay Between Host Immunity and Clostridium difficile PathogenesisU19AI090871 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YOUNG, VINCENT B · 2010 to 2014
$7.5M
Understanding the Lung Microbiome in HIV-Infected and HIV-uninfected individualsU01HL098961 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BECK, JAMES M, CURTIS, JEFFREY LOUIS · 2009 to 2013
$3.6M
Role of Fungal Microflora in Mucosal Tolerance/ImmunityR01AI064479 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUFFNAGLE, GARY B · 2005 to 2009
$1.8M
The role of Candida albicans biofilms in a novel rat model of denture stomatitisR01DE022069 · NIDCR · LSU HEALTH SCIENCES CENTER · PI NOVERR, MAIRI C · 2013 to 2017
$1.8M
Pulmonary bacterial microbiome-epithelial cell interactions in COPDR01HL114447 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUFFNAGLE, GARY B, MARTINEZ, FERNANDO J · 2012 to 2015
$1.5M
Impact of Candida Oxylipins on Host Immunity and Fungal BiologyR01AI072406 · NIAID · WAYNE STATE UNIVERSITY · PI NOVERR, MAIRI C · 2008 to 2011
$1.3M
The Role of the Microbiome in the Development/Prevention of Food AllergiesR21AI087869 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUFFNAGLE, GARY B · 2010 to 2011
$424k
Mucosal Mechanisms Linking Pulmonary and Gastrointestinal Inflammation/ImmunityR21AI083473 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUFFNAGLE, GARY B · 2009 to 2010
$412k
NHLBI NIH HHS R01 HL114447NHLBI NIH HHS R01HL114447NHLBI NIH HHS U01 HL098961NHLBI NIH HHS U01HL98961NIAID NIH HHS R01 AI064479NIAID NIH HHS R01 AI072406NIAID NIH HHS R01AI072406NIAID NIH HHS R21 AI083473NIAID NIH HHS R21 AI087869NIAID NIH HHS U19 AI090871NIAID NIH HHS U19AI090871NIDCR NIH HHS R01 DE022069NIDCR NIH HHS R01DE022069NIDDK NIH HHS P30 DK034933
6 · The paper itself

Abstract

The study of the fungal microbiota ('mycobiome') is a new and rapidly emerging field that lags behind our understanding of the bacterial microbiome. Every human has fungi as part of their microbiota, but the total number of fungal cells is orders of magnitude smaller than that of the bacterial microbiota. However, the impact of the mycobiome on human health is significant, especially as a reservoir for blooms of pathogenic microbes when the host is compromised and as a potential cofactor in inflammatory diseases and metabolic disorders.

Indexed as

MicrobiotaFungiHumans

Identifiers

PMID23685069
PMCPMC3708484
OpenAlexW2069773272

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.