Evidence map›Paper›PMID 23684877›Full record

ArticleNeuroImage2013

Function in the human connectome: task-fMRI and individual differences in behavior.

Deanna M Barch, Gregory C Burgess, Michael P Harms, Steven E Petersen, Bradley L Schlaggar, Maurizio Corbetta, Matthew F Glasser, Sandra Curtiss, Sachin Dixit, Cindy Feldt and 11 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in NeuroImage, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07024875 (Precision Neuroimaging of Parkinson's Disease), which is not on this map. Cited by 864 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
864citing papers in PubMed, 2 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07024875 recruitingnot on this mapstarted 2025, after this paper: background citation

Precision Neuroimaging of Parkinson's Disease

Typeobservational_patient_registrySponsorWashington University School of MedicineRan2025 to 2031Enrolled120ConditionsParkinsons Disease (PD)
3 · Its place in the literature

Who cites it

864 citing papers in PubMed, 2 syntheses or guidelines pooled it, 1,671 citations in OpenAlex.

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804 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 2 countries.

Deanna M BarchDepartment of Psychology, Washington University, St. Louis, MO 63130, USA. dbarch@artsci.wustl.edu
Gregory C Burgess
Michael P Harms
Steven E Petersen
Bradley L Schlaggar
Maurizio Corbetta
Matthew F Glasser
Sandra Curtiss
Sachin Dixit
Cindy Feldt
Dan Nolan
Edward Bryant
Tucker Hartley
Owen Footer
James M Bjork
Russ Poldrack
Steve Smith
Heidi Johansen-Berg
Abraham Z Snyder
David C Van Essen
WU-Minn HCP Consortium
Washington University in St. Louis · USUniversity of Oxford · GBNational Institute on Drug Abuse · USThe University of Texas at Austin · US

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
Non-invasive Multi-modal Parcellation of the Human Cerebral CortexF30MH097312 · NIMH · WASHINGTON UNIVERSITY · PI GLASSER, MATTHEW FREDERICK · 2012 to 2014
$105k
NIMH NIH HHS F30 MH097312NIMH NIH HHS U54 MH091657Wellcome Trust 090955Wellcome Trust 098369
6 · The paper itself

Abstract

The primary goal of the Human Connectome Project (HCP) is to delineate the typical patterns of structural and functional connectivity in the healthy adult human brain. However, we know that there are important individual differences in such patterns of connectivity, with evidence that this variability is associated with alterations in important cognitive and behavioral variables that affect real world function. The HCP data will be a critical stepping-off point for future studies that will examine how variation in human structural and functional connectivity play a role in adult and pediatric neurological and psychiatric disorders that account for a huge amount of public health resources. Thus, the HCP is collecting behavioral measures of a range of motor, sensory, cognitive and emotional processes that will delineate a core set of functions relevant to understanding the relationship between brain connectivity and human behavior. In addition, the HCP is using task-fMRI (tfMRI) to help delineate the relationships between individual differences in the neurobiological substrates of mental processing and both functional and structural connectivity, as well as to help characterize and validate the connectivity analyses to be conducted on the structural and functional connectivity data. This paper describes the logic and rationale behind the development of the behavioral, individual difference, and tfMRI batteries and provides preliminary data on the patterns of activation associated with each of the fMRI tasks, at both group and individual levels.

Indexed as

Models, NeurologicalTask Performance and AnalysisAdultBehaviorBrainConnectomeFemaleHumansMagnetic Resonance ImagingMaleModels, AnatomicNerve NetYoung AdultCognitiveConnectivityEmotionIndividual differencesPersonalitySensory and motor functionTask-fMRI

Identifiers

PMID23684877
PMCPMC4011498
OpenAlexW2071608556

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.