Evidence map›Paper›PMID 23684145›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2013

KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKD.

Sandra J Taler, Rajiv Agarwal, George L Bakris, Joseph T Flynn, Peter M Nilsson, Mahboob Rahman, Paul W Sanders, Stephen C Textor, Matthew R Weir, Raymond R Townsend

Open access · greenAbstract read
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 5 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 5 syntheses or guidelines pooled it, 196 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. BP and Renal Outcomes in Diabetic Kidney Disease: The Veterans Affairs Nephropathy in Diabetes Trial.Clinical journal of the American Society of Nephrology : CJASN · 2015
    Trial
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  12. Review
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 2 countries.

Sandra J TalerDivision of Nephrology and Hypertension, College of Medicine, Mayo Clinic, Rochester, MN, USA.
Rajiv Agarwal
George L Bakris
Joseph T Flynn
Peter M Nilsson
Mahboob Rahman
Paul W Sanders
Stephen C Textor
Matthew R Weir
Raymond R Townsend
Mayo Clinic · USCase Western Reserve University · USLund University · SERichard L. Roudebush VA Medical Center · USSeattle Children's Hospital · USUniversity of Alabama at Birmingham · USUniversity of Chicago · USUniversity of Maryland, Baltimore · USUniversity of Pennsylvania · US

Funding

UAB-UCSD O'Brien Core Center for Acute Kidney Injury ResearchP30DK079337 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AGARWAL, ANUPAM · 2008 to 2022
$18.3M
Limited Competition for the Continuation of the Chronic Renal Insufficiency CohorU01DK061021 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI RAHMAN, MAHBOOB · 2001 to 2025
$17.3M
The health status of Caucasian and African American living with kidney donorsU01AI069544 · NIAID · MAYO CLINIC ROCHESTER · PI TALER, SANDRA J · 2006 to 2010
$4.2M
Salt-Sensitive Hypertension/Hypertensive NephrosclerosisR01DK046199 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SANDERS, PAUL W. · 1992 to 2011
$2.9M
Live Unrelated Kidney Donor &Sibling Follow-up StudyR01DK066013 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI KASISKE, BERTRAM L · 2005 to 2005
$558k
Low Molecular Weight Protein NephrotoxicityI01BX001192 · VA · BIRMINGHAM VA MEDICAL CENTER · PI SANDERS, PAUL W. · 2011 to 2014
–
Novel Regulators of Vascular DiseaseIP1BX001595 · VA · BIRMINGHAM VA MEDICAL CENTER · PI AGARWAL, ANUPAM, CHEN, YABING · 2013 to 2016
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BLRD VA I01 BX001192BLRD VA IP1 BX001595NIAID NIH HHS 5U01AI069544NIAID NIH HHS U01 AI069544NIDDK NIH HHS 5U01DK061021-12NIDDK NIH HHS P30 DK079337NIDDK NIH HHS R01 DK046199NIDDK NIH HHS R01 DK-066013NIDDK NIH HHS R01 DK066013NIDDK NIH HHS U01 DK061021PHS HHS 268200900049C-0-0-1PHS HHS R01 PA07-070
6 · The paper itself

Abstract

In response to the 2012 KDIGO (Kidney Disease: Improving Global Outcomes) guideline for blood pressure management in patients with chronic kidney disease not on dialysis, the National Kidney Foundation organized a group of US experts in hypertension and transplant nephrology to review the recommendations and comment on their relevancy in the context of current US clinical practice and concerns. The overriding message was the dearth of clinical trial evidence to provide strong evidence-based recommendations. For patients with CKD with normal to mildly increased albuminuria, goal blood pressure has been relaxed to ≤140/90 mm Hg for both diabetic and nondiabetic patients. In contrast, KDIGO continues to recommend goal blood pressure ≤130/80 mm Hg for patients with chronic kidney disease with moderately or severely increased albuminuria and for all renal transplant recipients regardless of the presence of proteinuria, without supporting data. The expert panel thought the KDIGO recommendations were generally reasonable but lacking in sufficient evidence support and that additional studies are greatly needed.

Indexed as

Practice Guidelines as TopicBiomedical ResearchBlood PressureDiabetic NephropathiesHumansHypertensionRenal Insufficiency, Chronicblood pressureguidelineKidney Disease: Improving Global Outcomes (KDIGO)

Identifiers

PMID23684145
PMCPMC3929429
OpenAlexW2070854138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.