ArticleJournal of medical case reports2013
Acute embolic cerebral ischemia as an initial presentation of polycythemia vera: a case report.
Article in Journal of medical case reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- JAK2-positive erythrocytosis presenting with left occipital infarction in a young adult: a case report from a resource‑limited setting.Annals of medicine and surgery (2012) · 2026Article
- Acute cerebral ischemic stroke as a presentation of polycythemia vera: a case report and a review of literature.Annals of medicine and surgery (2012) · 2023Article
- Hemorrhagic transformation after acute ischemic stroke caused by polycythemia vera: Report of two case.World journal of clinical cases · 2021Article
- A case of canine renal lymphoma of granular lymphocytes with severe polycythemia.BMC veterinary research · 2021Article
- Characteristics of acute ischemic stroke in hospitalized patients in Tibet: a retrospective comparative study.BMC neurology · 2020Article
- Cerebrovascular Complications and Polycythaemia Vera.Pathology oncology research : POR · 2019Article
- Acute cerebrovascular event in a dog with polycythemia vera.The Canadian veterinary journal = La revue veterinaire canadienne · 2018Article
- Ischemic Stroke Caused by Secondary Polycythemia and Incidentally-Found Renal Cell Carcinoma: A Case Report.The American journal of case reports · 2018Article
- Recurrent ischaemic stroke unveils polycythaemia vera.BMJ case reports · 2015Article
- Partial Status Epilepticus in Cerebral Venous Sinus Thrombosis, Initial Manifestation of Polycythemia Vera.Annals of Indian Academy of NeurologyArticle
- The cerebral circulation and cerebrovascular disease II: Pathogenesis of cerebrovascular disease.Brain circulationReview
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPatients with polycythemia vera are at high risk for vaso-occlusive events including cerebral ischemia. Although unusual, acute ischemic stroke may be an initial presentation of polycythemia vera. It had been previously assumed that cerebral ischemic events were due to increased blood viscosity and platelet activation within the central nervous system arterial vessels. However, there are now a few isolated case reports of probable micro-embolic events originating from outside of the brain. This suggests unique management issues for these patients. CASE PRESENTATION: We present the case of a 57-year-old right-handed Caucasian male in excellent health who presented to the Emergency Department with acute right-handed clumsiness. Hematologic investigations revealed a hyperviscous state and magnetic resonance imaging was consistent with cerebral emboli. Symptoms rapidly improved with phlebotomy and hydration.
conclusionThe etiology of stroke in polycythemic patients is likely to be multifactorial. While hemodilution has been generally discredited for general stroke management, it is potentially beneficial for patients with polycythemia vera and euvolemic hemodilution should be considered for the polycythemic patient with acute cerebral ischemia.
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Registered trials
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