ArticleACS nano2013
Gold nanoparticle-based activatable probe for sensing ultralow levels of prostate-specific antigen.
Article in ACS nano, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Real-Time and Ultrasensitive Prostate-Specific Antigen Sensing Using Love-Mode Surface Acoustic Wave Immunosensor Based on MoSSensors (Basel, Switzerland) · 2024Article
- Advances in Prostate Cancer Biomarkers and Probes.Cyborg and bionic systems (Washington, D.C.) · 2024Review
- Corrigendum: Nano-Theranostics for the Sensing, Imaging and Therapy of Prostate Cancers.Frontiers in chemistry · 2022Article
- Gold Nanoparticles Based Optical Biosensors for Cancer Biomarker Proteins: A Review of the Current Practices.Frontiers in bioengineering and biotechnology · 2022Review
- Nano-Theranostics for the Sensing, Imaging and Therapy of Prostate Cancers.Frontiers in chemistry · 2022Review
- Controlled copper in situ growth-amplified lateral flow sensors for sensitive, reliable, and field-deployable infectious disease diagnostics.Biosensors & bioelectronics · 2021Article
- Self-powered cathodic photoelectrochemical aptasensor based on in situ-synthesized CuO-CuMikrochimica acta · 2020Article
- Nanozyme-assisted sensitive profiling of exosomal proteins for rapid cancer diagnosis.Theranostics · 2020Article
- Engineered Gold-Based Nanomaterials: Morphologies and Functionalities in Biomedical Applications. A Mini Review.Bioengineering (Basel, Switzerland) · 2019Review
- Paper-based fluorometric immunodevice with quantum-dot labeled antibodies for simultaneous detection of carcinoembryonic antigen and prostate specific antigen.Mikrochimica acta · 2019Article
- An Aggregation-Induced Emission-Based Indirect Competitive Immunoassay for Fluorescence "Turn-On" Detection of Drug Residues in Foodstuffs.Frontiers in chemistry · 2019Article
- Aptasensor based on fluorophore-quencher nano-pair and smartphone spectrum reader for on-site quantification of multi-pesticides.Biosensors & bioelectronics · 2018Article
- A Metal Chelator as a Plasmonic Signal-Generation Superregulator for Ultrasensitive Colorimetric Bioassays of Disease Biomarkers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Article
- Potential Applications of Nanotechnology in Urological Cancer.Frontiers in pharmacology · 2018Review
- Fluorometric competitive immunoassay for chlorpyrifos using rhodamine-modified gold nanoparticles as a label.Mikrochimica acta · 2017Article
- Phospholipase A2-Responsive Phosphate Micelle-Loaded UCNPs for Bioimaging of Prostate Cancer Cells.Scientific reports · 2017Article
- Surface Plasmon Resonance or Biocompatibility-Key Properties for Determining the Applicability of Noble Metal Nanoparticles.Materials (Basel, Switzerland) · 2017Review
- Nanomaterial-based biosensors for detection of prostate specific antigen.Mikrochimica acta · 2017Review
- Article
- Ultrasensitive fluorescence immunoassay for detection of ochratoxin A using catalase-mediated fluorescence quenching of CdTe QDs.Nanoscale · 2016Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
It is still in high demand to develop extremely sensitive and accurate clinical tools for biomarkers of interest for early diagnosis and monitoring of diseases. In this report, we present a highly sensitive and compatible gold nanoparticle (AuNP)-based fluorescence-activatable probe for sensing ultralow levels of prostate-specific antigen (PSA) in patient serum samples. The limit of detection of the newly developed probe for PSA was pushed down to 0.032 pg/mL, which is more than 2 orders of magnitude lower than that of the conventional fluorescence probe. The ultrahigh sensitivity of this probe was attributed to the high loading efficiency of the dyes on AuNP surfaces and high fluorescence quenching-unquenching abilities of the dye-AuNP pairs. The efficiency and robustness of this probe were investigated in patient serum samples, demonstrating the great potential of this probe in real-world applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.