ReviewJournal of toxicology and environmental health. Part B, Critical reviews2013
Environmental contaminant exposures and preterm birth: a comprehensive review.
Review in Journal of toxicology and environmental health. Part B, Critical reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 3 syntheses or guidelines pooled it, 163 citations in OpenAlex.
- Prenatal metal(loid) exposure and preterm birth: a systematic review of the epidemiologic evidence.Journal of exposure science & environmental epidemiology · 2025Pooled it
- Maternal Occupational Risk Factors and Preterm Birth: A Systematic Review and Meta-Analysis.Public health reviews · 2023Pooled it
- Environmental contaminants and preeclampsia: a systematic literature review.Journal of toxicology and environmental health. Part B, Critical reviews · 2018Pooled it
- Maternal Serum Nitrate and Nitrite Associations With Birth Outcomes: A Case-Control Study.GeoHealth · 2026Article
- Polycyclic aromatic hydrocarbons and perinatal outcomes: a scoping review.Pediatric research · 2026Review
- Oxidative Stress-Related Metabolomic Alterations in Pregnancy: Evidence from Exposure to Air Pollution, Metals/Metalloid, and Tobacco Smoke.Antioxidants (Basel, Switzerland) · 2025Review
- Impacts of Vehicle Emission Regulations and Local Congestion Policies on Birth Outcomes Associated with Traffic Air Pollution.Research report (Health Effects Institute) · 2025Article
- Ambient Toxic Air Contaminants in the Maternal Residential Area during Pregnancy and Cerebral Palsy in the Offspring.Environmental health perspectives · 2025Article
- Changes in traffic-related air pollution exposures and associations with adverse birth outcomes over 20 years in Texas.International journal of epidemiology · 2024Article
- An exploratory study on the association of multiple metals in serum with preeclampsia.Frontiers in public health · 2024Article
- Deleterious Biological Effects of Endocrine Disruptors: An Insight into Human Health Risks.Endocrine, metabolic & immune disorders drug targets · 2024Review
- Spillover effects of gestational age on sibling's literacy.Early child development and care · 2024Article
- Seasonal variation in air pollutant levels and its effects on the sex ratio at birth on Fukue island, Japan.BMC public health · 2023Article
- Preterm Birth and Metal Mixture Exposure among Pregnant Women from the Navajo Birth Cohort Study.Environmental health perspectives · 2023Article
- The pregnancy research on inflammation, nutrition, & city environment: systematic analyses study (PRINCESA) cohort, 2009-2015.European journal of epidemiology · 2023Article
- Temporal trends and predictors of phthalate, phthalate replacement, and phenol biomarkers in the LIFECODES Fetal Growth Study.Environment international · 2023Article
- Mediation effects of DNA methylation and hydroxymethylation on birth outcomes after prenatal per- and polyfluoroalkyl substances (PFAS) exposure in the Michigan mother-infant Pairs cohort.Clinical epigenetics · 2023Article
- Is residential proximity to polluted sites during pregnancy associated with preterm birth or low birth weight? Results from an integrated exposure database in North Carolina (2003-2015).Journal of exposure science & environmental epidemiology · 2023Article
- Metal mixtures modeling identifies birth weight-associated gene networks in the placentas of children born extremely preterm.Chemosphere · 2023Article
- Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Preterm birth is a significant public health concern, as it is associated with high risk of infant mortality, various morbidities in both the neonatal period and later in life, and a significant societal economic burden. As many cases are of unknown etiology, identification of the contribution of environmental contaminant exposures is a priority in the study of preterm birth. This is a comprehensive review of all known studies published from 1992 through August 2012 linking maternal exposure to environmental chemicals during pregnancy with preterm birth. Using PubMed searches, studies were identified that examined associations between preterm birth and exposure to five categories of environmental toxicants, including persistent organic pollutants, drinking-water contaminants, atmospheric pollutants, metals and metalloids, and other environmental contaminants. Individual studies were summarized and specific suggestions were made for future work in regard to exposure and outcome assessment methods as well as study design, with the recommendation of focusing on potential mediating toxicological mechanisms. In conclusion, no consistent evidence was found for positive associations between individual chemical exposures and preterm birth. By identifying limitations and addressing the gaps that may have impeded the ability to identify true associations thus far, this review can guide future epidemiologic studies of environmental exposures and preterm birth.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.