ArticleSurgical neurology international2013
Diagnostic yield of stereotactic needle-biopsies of sub-cubic centimeter intracranial lesions.
Article in Surgical neurology international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Non-contact Intraoperative Optical Imaging During Neurosurgical Procedures
Non-contact Intraoperative Optical Imaging During Spinal Procedures
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Clinical outcomes as a function of the number of samples taken during stereotactic needle biopsies: a meta-analysis.Journal of neuro-oncology · 2021Pooled it
- Outcomes of Laser Interstitial Thermal Therapy-Augmented Surgery in the Management of Subcortical Glioblastoma.Neurosurgery practice · 2026Article
- An Augmented Reality-Based Navigation System for Stereotactic Brain Biopsy with Multi-Objective Path Planning and Hybrid Registration.Brain sciences · 2026Article
- Accuracy and Diagnostic Yield of the New Albert-Wong Stereotactic Frame and Its Comparison with the Cosman-Robert-Wells Frame for Brain Biopsy.Journal of Korean Neurosurgical Society · 2026Article
- Magnetic resonance-guided stereotactic biopsy in intracranial lesions.Surgical neurology international · 2025Article
- Comparable safety profile between neuro-oncology procedures involving stereotactic needle biopsy (SNB) followed by laser interstitial thermal therapy (LITT) and LITT alone procedures.Journal of neuro-oncology · 2023Article
- Learning Curve Associated with ClearPoint Neuronavigation System: A Case Series.World neurosurgery: X · 2022Article
- Evaluation of 311 contemporary cases of stereotactic biopsies in patients with neoplastic and non-neoplastic lesions-diagnostic yield and management of non-diagnostic cases.Neurosurgical review · 2021Article
- Optical Brain Biopsy with a Fluorescence and Vessel Tracing Probe.Operative neurosurgery (Hagerstown, Md.) · 2021Article
- Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System (LAANTERN): 12-Month Outcomes and Quality of Life After Brain Tumor Ablation.Neurosurgery · 2020Observational
- Real-time MR-guided brain biopsy using 1.0-T open MRI scanner.European radiology · 2019Article
- 5-ALA fluorescence and laser Doppler flowmetry for guidance in a stereotactic brain tumor biopsy.Biomedical optics express · 2018Article
- Frame-based stereotactic biopsies using an intraoperative MR-scanner are as safe and effective as conventional stereotactic procedures.PloS one · 2018Article
- Article
- Application of stereotactic biopsy for diagnosing intracranial lesions in patients with AIDS in China: Report of 7 cases.Medicine · 2016Article
- Next-generation sequencing of tissue: A logical extension.Neurology(R) neuroimmunology & neuroinflammation · 2016Article
- A novel, integrated PET-guided MRS technique resulting in more accurate initial diagnosis of high-grade glioma.The neuroradiology journal · 2016Article
- Diagnostic Accuracy of PET, SPECT, and Arterial Spin-Labeling in Differentiating Tumor Recurrence from Necrosis in Cerebral Metastasis after Stereotactic Radiosurgery.AJNR. American journal of neuroradiology · 2015Article
- Achieving Higher Diagnostic Results in Stereotactic Brain Biopsy by Simple and Novel Technique.Open access Macedonian journal of medical sciences · 2015Article
- Extracellular vesicles as a platform for 'liquid biopsy' in glioblastoma patients.Expert review of molecular diagnostics · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStereotactic brain biopsies are widely used for establishing the diagnosis of intracranial lesions. Here we examine whether stereotactic biopsy of smaller brain lesions, defined for this study as being less than 1 cubic centimeter (1 cc) in volume, are associated with lowered diagnostic yield.
methodsWe conducted a retrospective analysis of 267 consecutive patients who underwent stereotactic brain biopsy between 2007 and 2011. Lesion volumes were calculated and were stratified by <1 or >1 cc.
resultsA total of 13 of 246 (5.2%) biopsies for lesions >1 cc resulted in nondiagnostic tissue or an incorrect diagnosis. In contrast, 5 of 21 (23.8%) biopsies for <1 cc lesions yielded nondiagnostic or incorrect diagnosis. Posthoc review of tissue from the <1 cc lesions suggests the neuropathologist's expertise in the handling and analysis of limited specimen as a critical parameter of successful diagnosis. The operative morbidities were low for both the <1 and >1 cc biopsies (0% and 1%, respectively).
conclusionThis study demonstrates that stereotactic cerebral biopsy of lesions less than a cubic centimeter in volume results in a lower diagnostic yield versus larger lesions (76.2% versus 94.8%). While auxiliary measures may be taken to improve diagnostic yield, these patients may be best managed in a specialized center with experienced stereotactic neurosurgeons and neuropathologists.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.