Evidence map›Paper›PMID 23682226›Full record

Trial reportThe Korean journal of internal medicine2013

A comparison of the BISAP score and serum procalcitonin for predicting the severity of acute pancreatitis.

Byung Geun Kim, Myung Hwan Noh, Choong Heon Ryu, Hwa Seong Nam, Su Mi Woo, Seung Hee Ryu, Jin Seok Jang, Jong Hun Lee, Seok Ryeol Choi, Byeong Ho Park

Abstract readClinical TrialComparative Study
In one paragraph

Trial report in The Korean journal of internal medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. The Diagnostic Value of Procalcitonin in Patients with Severe Acute Pancreatitis: A Meta-Analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022
    Pooled it
  2. Pooled it
  3. Evaluating the Ability of the Bedside Index for Severity of Acute Pancreatitis Score to Predict Severe Acute Pancreatitis: A Meta-Analysis.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2016
    Pooled it
  4. Pooled it
  5. Article
  6. Prediction Models of Severity in Acute Biliary Pancreatitis.Diagnostics (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Turkish Society of Gastroenterology: Pancreas Working Group, Acute Pancreatitis Committee Consensus Report.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Article
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  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Early phase of acute pancreatitis: Assessment and management.World journal of gastrointestinal pathophysiology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Byung Geun KimDivision of Gastroenterology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.
Myung Hwan Noh
Choong Heon Ryu
Hwa Seong Nam
Su Mi Woo
Seung Hee Ryu
Jin Seok Jang
Jong Hun Lee
Seok Ryeol Choi
Byeong Ho Park

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe bedside index of severity in acute pancreatitis (BISAP) is a new, convenient, prognostic multifactorial scoring system. As more data are needed before clinical application, we compared BISAP, the serum procalcitonin (PCT), and other multifactorial scoring systems simultaneously.

methodsFifty consecutive acute pancreatitis patients were enrolled prospectively. Blood samples were obtained at admission and after 48 hours and imaging studies were performed within 48 hours of admission. The BISAP score was compared with the serum PCT, Ranson's score, and the acute physiology and chronic health examination (APACHE)-II, Glasgow, and Balthazar computed tomography severity index (BCTSI) scores. Acute pancreatitis was graded using the Atlanta criteria. The predictive accuracy of the scoring systems was measured using the area under the receiver-operating curve (AUC).

resultsThe accuracy of BISAP (≥ 2) at predicting severe acute pancreatitis was 84% and was superior to the serum PCT (≥ 3.29 ng/mL, 76%) which was similar to the APACHE-II score. The best cutoff value of BISAP was 2 (AUC, 0.873; 95% confidence interval, 0.770 to 0.976; p < 0.001). In logistic regression analysis, BISAP had greater statistical significance than serum PCT.

conclusionsBISAP is more accurate for predicting the severity of acute pancreatitis than the serum PCT, APACHE-II, Glasgow, and BCTSI scores.

Indexed as

Severity of Illness IndexBiomarkersCalcitoninCalcitonin Gene-Related PeptideFemaleHumansLogistic ModelsMaleMiddle AgedPancreatitisPrognosisProspective StudiesProtein PrecursorsROC CurveBiomarkersCALCA protein, humanCalcitoninCalcitonin Gene-Related PeptideProtein PrecursorsAcute pancreatitisPrognosisSerum procalcitoninSeverity

Identifiers

PMID23682226
PMCPMC3654130

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.