Evidence map›Paper›PMID 23681888›Full record

ReviewFrontiers of medicine2013

Inflammation and liver tumorigenesis.

Beicheng Sun, Michael Karin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Frontiers of medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
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  12. Sera Anti-P53 Antibody Provides New Information Which Explains the Link Between Diabetes and Cancer.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  13. Article
  14. TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Apoptosis and necroptosis in the liver: a matter of life and death.Nature reviews. Gastroenterology & hepatology · 2018
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Beicheng SunLiver Transplantation Center of the First Affiliated Hospital and Cancer Center, Nanjing Medical University, Nanjing, China. sunbc@njmu.edu.cn
Michael Karin
Nanjing Medical University · CNUniversidad Católica Santo Domingo · DO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation has been considered as one of the hallmarks of cancer, and chronic hepatitis is a major cause of liver cancer. This review will focus on the pathogenic role of inflammation in hepatocarcinogenesis and will discuss recent advances in understanding the chronic hepatitis-liver cancer link based on hot spots in liver cancer research, including cellular interaction, cytokines, microRNA and stem cells. All of these mechanisms should be taken into consideration because they are crucial for the development of more efficacious therapeutic strategies for preventing and treating human chronic hepatitis and hepatocellular carcinoma.

Indexed as

Carcinoma, HepatocellularCell Transformation, NeoplasticCytokinesHepatitisHumansInflammationLiver NeoplasmsMicroRNAsCytokinesMicroRNAs

Identifiers

PMID23681888
OpenAlexW2060163841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.