Trial reportRheumatology (Oxford, England)2013
Predictors of self-reported health-related quality of life in systemic lupus erythematosus.
Trial report in Rheumatology (Oxford, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Perceived and Objective Physical Function in 2 United States Population-Based Cohorts of Adults With Systemic Lupus Erythematosus.The Journal of rheumatology · 2026Article
- Lupus Remission: How Do Patient and Physician Perceptions Align?Healthcare (Basel, Switzerland) · 2026Article
- Age-related patterns of organ damage impact on health-related quality of life in SLE.Lupus science & medicine · 2025Article
- Impact of quality of life on overall work productivity impairment and activity impairment of patients with systemic lupus erythematosus: the PEONY study.Lupus science & medicine · 2025Article
- Racial differences in clinical trial perceptions among a large, predominantly Black cohort of people with systemic lupus erythematosus in the Southeastern USA.Lupus science & medicine · 2025Article
- Predicting EQ-5D full health state in systemic lupus erythematosus using machine learning algorithms.Rheumatology advances in practice · 2025Article
- Perspectives of Rheumatologists on the Type 1 and 2 Systemic Lupus Erythematosus Model.ACR open rheumatology · 2024Article
- Musculoskeletal symptoms in systemic lupus erythematosus patients and their impact on health-related quality of life.BMC musculoskeletal disorders · 2024Article
- Article
- Development and psychometric evaluation of a physician global assessment for type 2 systemic lupus erythematosus symptoms.Lupus science & medicine · 2023Article
- The impact of social determinants of health on the presentation, management and outcomes of systemic lupus erythematosus.Rheumatology (Oxford, England) · 2023Review
- Fibromyalgia, mood disorders, cognitive test results, cognitive symptoms and quality of life in systemic lupus erythematosus.Rheumatology (Oxford, England) · 2022Article
- Psychological Implications to the Therapy of Systemic Lupus Erythematosus.International journal of environmental research and public health · 2022Review
- Intermittent and Persistent Type 2 lupus: patient perspectives on two distinct patterns of Type 2 SLE symptoms.Lupus science & medicine · 2022Article
- The use of patient-reported outcome measures to classify type 1 and 2 systemic lupus erythematosus activity.Lupus · 2022Article
- Severe flares are associated with a poorer health-related quality of life (HRQoL) in patients with SLE: data from the Almenara Lupus Cohort.Lupus science & medicine · 2022Article
- Factors associated with self-reported capacity to walk, jog and run in individuals with systemic lupus erythematosus.Archives of rheumatology · 2021Article
- Predictors of health-related quality of life in musculoskeletal disease patients: a longitudinal analysis.Therapeutic advances in musculoskeletal disease · 2021Article
- Adverse Health-Related Quality of Life Outcome Despite Adequate Clinical Response to Treatment in Systemic Lupus Erythematosus.Frontiers in medicine · 2021Article
- Predictive factors of quality of life among systemic lupus erythematosus patients in Thailand: a web-based cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveThe Medical Outcomes Short Form-36 Survey (SF-36) has been widely used as a measure of health-related quality of life (HRQOL) in different populations. SLE patients have consistently reported lower scores compared with the general population. The objective of our study was to identify predictors of HRQOL using SF-36 among patients with SLE enrolled in a 2-year randomized controlled trial (RCT).
methodsWe analysed 200 SLE patients enrolled in the Lupus Atherosclerosis Prevention Study (LAPS), an RCT of atorvastatin vs placebo, who completed SF-36 at qualifying, 12- and 24-month (final) visits.
resultsAt baseline, mean SF-36 domain scores were lower than those of age- and gender-matched population norms. There was no statistical difference reported between Physical Component Summary (PCS), Mental Component Summary and eight domain scores in the atorvastatin vs placebo group at 2 years. In multiple regression analyses, African American patients reported significantly lower scores in Physical Functioning compared with Caucasians. The presence of FM was significantly associated with lower scores in physical functioning, role physical, bodily pain, general health, vitality, social functioning and lower overall mean PCS scores. The Physician's Global Assessment of disease activity was associated with multiple SF-36 domains in univariate analysis.
conclusionThis longitudinal study confirmed lower scores reported across all SF-36 domains. No one explanatory variable was independently associated with all domain scores. FM was independently associated with poorer HRQOL in most domains, underscoring the need for effective treatments for FM in SLE.
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