Evidence map›Paper›PMID 23680940›Full record

SynthesisEpidemiology (Cambridge, Mass.)2013

Mediterranean diet, cognitive function, and dementia: a systematic review.

Ilianna Lourida, Maya Soni, Joanna Thompson-Coon, Nitin Purandare, Iain A Lang, Obioha C Ukoumunne, David J Llewellyn

Registry-linked trialAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Epidemiology (Cambridge, Mass.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04204239 (A Review of Test Procedures From Different Health Care Professions With Regard to Their Suitability for the Early Detection of Cognitive Impairments in Persons Aged 60 and Older), which is not on this map. Cited by 221 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
221citing papers in PubMed, 15 pooled it
44.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04204239 unknown statusnot on this mapstarted 2020, after this paper: background citation

A Review of Test Procedures From Different Health Care Professions With Regard to Their Suitability for the Early Detection of Cognitive Impairments in Persons Aged 60 and Older: A Validation Study

TypeobservationalSponsorFH Joanneum Gesellschaft mbHRan2020 to 2023Enrolled300ConditionsCognitive Decline, Cognitive Deficit, Cognitive Impairment
3 · Its place in the literature

Who cites it

221 citing papers in PubMed, 15 syntheses or guidelines pooled it, 503 citations in OpenAlex.

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161 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ilianna LouridaPeninsula Collaboration for Leadership in Applied Health Research and Care, University of Exeter Medical School, Exeter, United Kingdom.
Maya Soni
Joanna Thompson-Coon
Nitin Purandare
Iain A Lang
Obioha C Ukoumunne
David J Llewellyn
Peninsula College of Medicine and Dentistry · GB

Funding

Department of Health
6 · The paper itself

Abstract

backgroundAdherence to a Mediterranean diet has been associated with lower risk of various age-related diseases including dementia. Although narrative reviews have been published, no systematic review has synthesized studies on the association between Mediterranean diet adherence and cognitive function or dementia.

methodsWe conducted a systematic review of 11 electronic databases (including Medline) of published articles up to January 2012. Reference lists, selected journal contents, and relevant websites were also searched. Study selection, data extraction, and quality assessment were performed independently by two reviewers using predefined criteria. Studies were included if they examined the association between a Mediterranean diet adherence score and cognitive function or dementia.

resultsTwelve eligible papers (11 observational studies and one randomized controlled trial) were identified, describing seven unique cohorts. Despite methodological heterogeneity and limited statistical power in some studies, there was a reasonably consistent pattern of associations. Higher adherence to Mediterranean diet was associated with better cognitive function, lower rates of cognitive decline, and reduced risk of Alzheimer disease in nine out of 12 studies, whereas results for mild cognitive impairment were inconsistent.

conclusionsPublished studies suggest that greater adherence to Mediterranean diet is associated with slower cognitive decline and lower risk of developing Alzheimer disease. Further studies would be useful to clarify the association with mild cognitive impairment and vascular dementia. Long-term randomized controlled trials promoting a Mediterranean diet may help establish whether improved adherence helps to prevent or delay the onset of Alzheimer disease and dementia.

Indexed as

Diet, MediterraneanAgedCognitionDementiaFemaleHumansMaleMiddle AgedRandomized Controlled Trials as Topic

Identifiers

PMID23680940
OpenAlexW2073294247

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.