Evidence map›Paper›PMID 23680639›Full record

ReviewDevelopmental and comparative immunology2014

Viruses and antiviral immunity in Drosophila.

Jie Xu, Sara Cherry

Open access · greenAbstract readReview
In one paragraph

Review in Developmental and comparative immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 144 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Characterization of Cross-Species Transmission ofLife (Basel, Switzerland) · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Frontiers in cellular and infection microbiology · 2022
    Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jie XuDepartment of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
Sara Cherry
University of Pennsylvania · US

Funding

Vaccine strategy for broad spectrum protection agains non-typhoidal salmonellU54AI057168 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI LEVINE, MYRON MAX · 2003 to 2013
$91.5M
The role of autophagy in innate anti-viral immunity in DrosophilaR01AI074951 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CHERRY, SARA · 2007 to 2017
$4.2M
Dissecting the alphavirus entry receptor NRAMPR01AI095500 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CHERRY, SARA · 2012 to 2015
$1.9M
Defining the determinants on the alphavirus receptor NRAMP required for virus binR21AI103441 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CHERRY, SARA · 2013 to 2014
$440k
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI074951NIAID NIH HHS R01AI074951NIAID NIH HHS R01 AI095500NIAID NIH HHS R01AI095500NIAID NIH HHS R21 AI103441NIAID NIH HHS U54 AI057168NIAID NIH HHS U54AI057168
6 · The paper itself

Abstract

Viral pathogens present many challenges to organisms, driving the evolution of a myriad of antiviral strategies to combat infections. A wide variety of viruses infect invertebrates, including both natural pathogens that are insect-restricted, and viruses that are transmitted to vertebrates. Studies using the powerful tools in the model organism Drosophila have expanded our understanding of antiviral defenses against diverse viruses. In this review, we will cover three major areas. First, we will describe the tools used to study viruses in Drosophila. Second, we will survey the major viruses that have been studied in Drosophila. And lastly, we will discuss the well-characterized mechanisms that are active against these diverse pathogens, focusing on non-RNAi mediated antiviral mechanisms. Antiviral RNAi is discussed in another paper in this issue.

Indexed as

AnimalsAntigens, ViralArbovirusesDrosophila melanogasterDrosophila ProteinsGene Expression ProfilingHost-Pathogen InteractionsHumansImmunityModels, AnimalPicornaviridaeRNA InterferenceSignal TransductionToll-Like ReceptorsAntigens, ViralDrosophila Proteinsimd protein, DrosophilaToll-Like ReceptorsAntiviralArbovirusArthropod-borneDrosophilaImmunityVirus

Identifiers

PMID23680639
PMCPMC3826445
OpenAlexW1995130141

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.