ArticleResearch in microbiology2013
Genetic characterization of moaB mutants of Escherichia coli.
Article in Research in microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- MoaB2, a newly identified transcription factor, binds to σJournal of bacteriology · 2024Article
- MoaB1 Homologs Contribute to Biofilm Formation and Motility by Pseudomonas aeruginosa and Escherichia coli.Journal of bacteriology · 2023Article
- Use of Transposon Directed Insertion-Site Sequencing to Probe the Antibacterial Mechanism of a Model Honey onFrontiers in microbiology · 2021Article
- Iron-Dependent Regulation of Molybdenum Cofactor Biosynthesis Genes in Escherichia coli.Journal of bacteriology · 2019Article
- A tool named Iris for versatile high-throughput phenotyping in microorganisms.Nature microbiology · 2017Article
- Biosynthesis and Insertion of the Molybdenum Cofactor.EcoSal Plus · 2015Review
- Structural basis of thermal stability of the tungsten cofactor synthesis protein MoaB from Pyrococcus furiosus.PloS one · 2014Article
- TusA (YhhP) and IscS are required for molybdenum cofactor-dependent base-analog detoxification.MicrobiologyOpen · 2013Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The moaABCDE operon of Escherichia coli encodes enzymes essential for the biosynthesis of the molybdenum cofactor (Moco). However, the role of the moaB gene within this operon has remained enigmatic. Here, we have investigated the effect of moaB defects on two phenotypes diagnostic for Moco-deficiency: chlorate-resistance and sensitivity to the base analog 6-N-hydroxylaminopurine (HAP). We found that transposon insertions in moaB caused partial Moco-deficiency associated with chlorate-resistance, but not for HAP-sensitivity. On the other hand, in-frame deletions of moaB, or moaB overexpression, had no effect on either phenotype. Our combined data are consistent with the lack of any role for MoaB in Moco biosynthesis in E. coli.
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Registered trials
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