Evidence map›Paper›PMID 23680145›Full record

ReviewCancer cell2013

Tumor cell dissemination: emerging biological insights from animal models and cancer patients.

Yibin Kang, Klaus Pantel

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancer cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 233 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
233citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

233 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Drosophila Intestine as a Model to Study Tumors.Advances in experimental medicine and biology · 2025
    Review
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173 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yibin KangDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. ykang@princeton.edu
Klaus Pantel

Funding

Metadherin in Metastasis and Chemoresistance of Breast CancerR01CA134519 · NCI · PRINCETON UNIVERSITY · PI KANG, YIBIN · 2008 to 2012
$1.6M
The Role of miRNAs in Epithelial-Mesenchymal Transition and MetastasisR01CA141062 · NCI · PRINCETON UNIVERSITY · PI KANG, YIBIN · 2010 to 2014
$1.6M
NCI NIH HHS R01 CA134519NCI NIH HHS R01 CA141062
6 · The paper itself

Abstract

Circulating tumor cells (CTCs) and disseminated tumor cells (DTCs) are increasingly recognized for their potential utility in disease monitoring and therapeutic targeting. The clinical application of CTC/DTC requires better understanding of the biological mechanisms behind tumor dissemination, the survival of DTCs, and their activation to aggressive growth from dormancy. Recent research using animal models of DTCs and CTCs have provided novel insights into these processes. Here, we discuss these findings in the context of results obtained from the clinical analyses of CTCs and DTCs, which demonstrate that the animal models mimic, in many aspects, the complex situation in patients.

Indexed as

AnimalsCell SurvivalDisease Models, AnimalEpithelial-Mesenchymal TransitionHumansMiceNeoplasm InvasivenessNeoplasm MetastasisNeoplastic Cells, Circulating

Identifiers

PMID23680145
PMCPMC3667710

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.