ArticleBMC gastroenterology2013
A large nationwide population-based case-control study of the association between intussusception and later celiac disease.
Article in BMC gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 22 citations in OpenAlex.
- Intussusception in children with celiac disease.Journal of family medicine and primary care · 2024Article
- Adult intussusception: A case series and review.World journal of gastrointestinal endoscopy · 2017Article
- A rare association of intussusception and celiac disease in a child.Sao Paulo medical journal = Revista paulista de medicina · 2016Article
- Association between Celiac Disease and Intussusceptions in Children: Two Case Reports and Literature Review.Pediatric gastroenterology, hepatology & nutrition · 2013Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundCase reports and case series studies suggest a positive association between intussusception and celiac disease (CD).
methodsWe contacted Sweden's 28 pathology departments and obtained data on 29,096 patients with biopsy-verified CD (equal to Marsh stage 3) through biopsy reports. Patients with CD were matched for age, sex, calendar period and county of residence with up to five reference individuals from the general population (n=144,522). Cases of intussusception were identified from nationwide inpatient, hospital-based outpatient and day-surgery data from the Swedish Patient Register.Odds ratios (ORs) for future CD in patients with intussusception were estimated using conditional logistic regression.
results34 (0.12%) individuals with CD had a diagnosis of intussusception vs. 143 (0.10%) reference individuals, suggesting that intussusception was not a risk factor for later CD (OR=1.17; 95% confidence interval (CI)=0.82-1.67). The OR for CD in patients with at least two records of intussusception was 0.40 (95% CI=0.06-2.99).In contrast, a post-hoc analysis showed that CD was associated with a statistically significantly increased risk of intussusception after CD diagnosis (hazard ratio=1.95; 95% CI=1.01-3.77); however, this analysis was based on only 12 cases with both CD and intussusception.
conclusionWe found no association between intussusception and future CD; and a mostly modest increased risk of intussusception after a diagnosis of CD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.