ArticlePhysical review letters2013
Glucose suppresses biological ferroelectricity in aortic elastin.
Article in Physical review letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 75 citations in OpenAlex.
- Exploring the piezoelectric phenomenon: From polymers to human tissues and advanced applications in tissue engineering.Bioactive materials · 2026Review
- Design and Manufacturing of Piezoelectric Biomaterials for Bioelectronics and Biomedical Applications.Chemical reviews · 2025Review
- Open Challenges and Opportunities in Piezoelectricity for Tissue Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Ultrasound-activated piezoelectric biomaterials for cartilage regeneration.Ultrasonics sonochemistry · 2025Review
- Ferroelectric and Non-Linear Optical Nanofibers by Electrospinning: From Inorganics to Molecular Crystals.Nanomaterials (Basel, Switzerland) · 2025Review
- Advanced Materials for Energy Harvesting and Soft Robotics: Emerging Frontiers to Enhance Piezoelectric Performance and Functionality.Advanced materials (Deerfield Beach, Fla.) · 2024Review
- Natural Piezoelectric Biomaterials: A Biocompatible and Sustainable Building Block for Biomedical Devices.ACS nano · 2022Review
- Manipulation of coacervate droplets with an electric field.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The intrinsic piezoelectric properties of materials - a review with a focus on biological materials.RSC advances · 2021Review
- Recent Progress in the Nanoscale Evaluation of Piezoelectric and Ferroelectric Properties via Scanning Probe Microscopy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- Advancing Versatile Ferroelectric Materials Toward Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- Correlation between polar surface area and bioferroelectricity in DNA and RNA nucleobases.The European physical journal. E, Soft matter · 2018Article
- The Coupled Bio-Chemo-Electro-Mechanical Behavior of Glucose Exposed Arterial Elastin.Journal of physics D: Applied physics · 2017Article
- Supramolecular ferroelectrics.Nature chemistry · 2015Review
- Ferroelectric switching of elastin.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Molecular ferroelectrics: where electronics meet biology.Physical chemistry chemical physics : PCCP · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Elastin is an intriguing extracellular matrix protein present in all connective tissues of vertebrates, rendering essential elasticity to connective tissues subjected to repeated physiological stresses. Using piezoresponse force microscopy, we show that the polarity of aortic elastin is switchable by an electrical field, which may be associated with the recently discovered biological ferroelectricity in the aorta. More interestingly, it is discovered that the switching in aortic elastin is largely suppressed by glucose treatment, which appears to freeze the internal asymmetric polar structures of elastin, making it much harder to switch, or suppressing the switching completely. Such loss of ferroelectricity could have important physiological and pathological implications from aging to arteriosclerosis that are closely related to glycation of elastin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.