Evidence map›Paper›PMID 23679023›Full record

ReviewDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

Genetic and cellular mechanisms of the formation of esophageal atresia and tracheoesophageal fistula.

I J Jacobs, J Que

Open access · bronzeAbstract readReview
In one paragraph

Review in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Development pattern of tracheal cartilage in human embryos.Clinical anatomy (New York, N.Y.) · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. [Research progress on transcription factors and signal pathways involved in congenital esophageal atresia].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2018
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

I J JacobsDepartment of Biology, University of Rochester, Rochester, New York 14642, USA.
J Que
University of Rochester · US

Funding

The role of transcription factor Sox2 in the homeostasis of the adult esophagusR00DK082650 · NIDDK · UNIVERSITY OF ROCHESTER · PI QUE, JIANWEN · 2012 to 2013
$483k
The Role of transcription factor Sox2 in the homeostasis of the adult esophagusK99DK082650 · NIDDK · UNIVERSITY OF ROCHESTER · PI QUE, JIANWEN · 2010 to 2011
$161k
NIDDK NIH HHS DK082650NIDDK NIH HHS K99 DK082650NIDDK NIH HHS R00 DK082650
6 · The paper itself

Abstract

Foregut separation involves dynamic changes in the activities of signaling pathways and transcription factors. Recent mouse genetic studies demonstrate that some of these pathways interact with each other to form a complex network, leading to a unique dorsal-ventral patterning in the early foregut. In this review, it is discussed how this unique dorsal-ventral patterning is set prior to the foregut separation and how disruption of this patterning affects the separation process. Roles of downstream targets of these pathways in regulating separation at cellular and molecular levels would be discussed further. Understanding the mechanism of normal separation process will provide insights into the pathobiology of a relatively common birth defect, esophageal atresia with/without tracheoesophageal fistula.

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsBiomarkersBone Morphogenetic ProteinsEsophageal AtresiaHedgehog ProteinsHumansMiceMutationSOXB1 Transcription FactorsTracheoesophageal FistulaWnt Signaling PathwayBiomarkersBone Morphogenetic ProteinsHedgehog ProteinsSOX2 protein, humanSox2 protein, mouseSOXB1 Transcription Factors

Identifiers

PMID23679023
PMCPMC4321969
OpenAlexW1833486604

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.