ArticlePsychological science2013
Retinal vessel caliber and lifelong neuropsychological functioning: retinal imaging as an investigative tool for cognitive epidemiology.
Article in Psychological science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Look into my eyes: What can eye-based measures tell us about the relationship between physical activity and cognitive performance?Journal of sport and health science · 2023Pooled it
- Advancing Brain and Body Vascular Imaging in Bipolar Disorder: A Report From the International Society for Bipolar Disorders Vascular Task Force.Bipolar disorders · 2026Review
- Evolution of Oculomics: From Naked Eye Observations to Artificial Intelligence over 100 Years.Ophthalmology science · 2026Article
- Retinal vessel caliber and cognitive performance: the multi-ethnic study of atherosclerosis (MESA).Scientific reports · 2024Article
- The Risk of Retinal Vein Occlusion in Young Patients with Mental Disorders: A Nationwide Cohort Study.Journal of clinical medicine · 2023Article
- The Dunedin study after half a century: reflections on the past, and course for the future.Journal of the Royal Society of New Zealand · 2023Article
- Neurostructural correlates of retinal microvascular caliber in adolescent bipolar disorder.JCPP advances · 2021Article
- A deep-learning system for the assessment of cardiovascular disease risk via the measurement of retinal-vessel calibre.Nature biomedical engineering · 2021Article
- Retinal Microvasculature in Schizophrenia.Eye and brain · 2021Article
- Denser Retinal Microvascular Network Is Inversely Associated With Behavioral Outcomes and Sustained Attention in Children.Frontiers in neurology · 2021Article
- Central arterial stiffness and retinal vessel calibers: the Atherosclerosis Risk in Communities Study-Neurocognitive Study.Journal of hypertension · 2020Article
- Retinal Microvascular Changes in Subtypes of Ischemic Stroke.Frontiers in neurology · 2020Article
- Retinal Morphometric Markers of Crystallized and Fluid Intelligence Among Adults With Overweight and Obesity.Frontiers in psychology · 2018Article
- Article
- Retinal microvascular network geometry and cognitive abilities in community-dwelling older people: The Lothian Birth Cohort 1936 study.The British journal of ophthalmology · 2017Article
- Challenge of cancer in the elderly.ESMO open · 2016Review
- Quantification of biological aging in young adults.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Schizophrenia and the eye.Schizophrenia research. Cognition · 2015Article
- Retinal microvessels reflect familial vulnerability to psychotic symptoms: A comparison of twins discordant for psychotic symptoms and controls.Schizophrenia research · 2015Article
- The Dunedin Multidisciplinary Health and Development Study: overview of the first 40 years, with an eye to the future.Social psychiatry and psychiatric epidemiology · 2015Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Why do more intelligent people live healthier and longer lives? One possibility is that intelligence tests assess health of the brain, but psychological science has lacked technology to evaluate this hypothesis. Digital retinal imaging, a new, noninvasive method to visualize microcirculation in the eye, may reflect vascular conditions in the brain. We studied the association between retinal vessel caliber and neuropsychological functioning in the representative Dunedin birth cohort. Wider venular caliber was associated with poorer neuropsychological functioning at midlife, independently of potentially confounding factors. This association was not limited to any specific test domain and extended to informants' reports of cohort members' cognitive difficulties in everyday life. Moreover, wider venular caliber was associated with lower childhood IQ tested 25 years earlier. The findings indicate that retinal venular caliber may be an indicator of neuropsychological health years before the onset of dementing diseases and suggest that digital retinal imaging may be a useful investigative tool for psychological science.
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Registered trials
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